Results 181 to 190 of about 1,563,368 (312)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Temporary frame coil technique for ruptured vertebral artery dissection involving major branch presentation: illustrative cases. [PDF]

J Neurosurg Case Lessons
Nakazato K, Imai T, Kawashima T, Matsumoto M.   +3 more
europepmc   +1 more source

LBM, a useful tool for mesoscale modelling of single phase and multiphase flow – the variety of applications and approaches at Nottingham

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
Zu, Y, 2nd Micro and Nano Flows Conference (MNF2009), Dong, B, Yan, Y   +3 more
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Optimizing Cardiac Inpatient Flow and Resource Allocation in Low-Resource Settings Using Queuing Theory: Insights From a Tertiary Hospital in Bangladesh. [PDF]

Public Health Chall
Uddin MB, Rahman K, Asaduzzaman M, Rahman ST, Hossain MS, Mostafa MS.   +5 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Toward standardized guidelines for distal perfusion cannulae in V-A ECMO and ECPELLA: timing, sizing, monitoring, and management. [PDF]

J Extra Corpor Technol
Pervaiz Butt S, Abdulaziz S, Razzaq N, Kumar A, Farheen M, Khalil R, Kakar V, Darr U, Bhatnagar G.   +8 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Flow Charts for Critical Thinking

Informal Logic, 2000
Daniel E. Flage
doaj   +1 more source

Hemodynamics in heart: the critical role of hemodynamics in myocardial tissue development and regenerative remodeling. [PDF]

Int J Cardiol Heart Vasc
Zhang R, Sun X, Liu Y, Meng Y, Zheng Y, Zhang C, Wang S.   +6 more
europepmc   +1 more source