Results 101 to 110 of about 8,178,562 (344)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Радиационная гигиена, 2017 The article is dedicated to comparison of different approaches to population exposure limitation at the example of external exposure of population living on territories contaminated after the accident at Chernobyl NPP.
V. Yu. Golikov
doaj
On the Analysis and Assessment of First‐Order Group Contribution Models for the Calculation of Normal Boiling Point and Critical Properties of Pure Compounds [PDF]
, 2022 V. Villazón-León +2 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Existence of three solutions for higher order BVP with parameters via Morse theory
Electronic Journal of Differential Equations, 2016 We prove the existence of at least three solutions to a general Lidstone problem using the Morse Theory.
Mariusz Jurkiewicz, Bogdan Przeradzki
doaj
Pilot and Feasibility StudiesObjective The overall objective of our research is to determine in children with septic shock whether the use of a fluid-sparing strategy results in improved clinical outcomes without an increased risk of adverse events compared to usual care.
Melissa J. Parker +5 more
doaj +1 more source
A Remark on the Renormalization Group Equation for the Penner Model
, 1994 It is possible to extract values for critical couplings and gamma_string in matrix models by deriving a renormalization group equation for the variation of the of the free energy as the size N of the matrices in the theory is varied.
A. Krzywicki +30 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Multiple solutions of nonlinear fractional elliptic equations via Morse theory
Electronic Journal of Differential Equations, 2017 This article concerns the existence and multiplicity of weak solutions of the nonlinear fractional elliptic problem. We extend some well known results of semilinear Laplacian equations to the nonlocal fractional setting. Using the variational methods
Wei Qi, Lin Zhao, Xingjie Yan
doaj
Intensive Care Medicine ExperimentalOpen-lung ventilation during cardiopulmonary bypass (CPB) in patients undergoing heart transplantation (HTx) is a potential strategy to mitigate postoperative acute respiratory distress syndrome (ARDS).
Varun Karnik +29 more
doaj +1 more source