Results 91 to 100 of about 3,452,336 (316)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Emerging Voices: Critical Social Research by European Group Postgraduate and Early Career Researchers

, 2017
This collection introduces the scholarly and activist work currently being undertaken by twenty-six emerging voices in the European Group for the Study of Deviance and Social Control.

core  

The effects of normovolemic anemia and blood transfusion on cerebral microcirculation after severe head injury

Intensive Care Medicine Experimental, 2018
Background Cerebral regional microcirculation is altered following severe head injury. In addition to tissue disruption, partial pressure of tissue oxygenation is impaired due to an increase in the oxygen tissue gradient.
Judith Bellapart, Kylie Cuthbertson, Kimble Dunster, Sara Diab, David G. Platts, Christopher Raffel, Levon Gabrielian, Adrian Barnett, Jennifer Paratz, Rob Boots, John F. Fraser   +10 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Existence of two nontrivial solutions for semilinear elliptic problems

Electronic Journal of Differential Equations, 2006
This paper concerns the existence of multiple nontrivial solutions for some nonlinear problems. The first nontrivial solution is found using a minimax method, and the second by computing the Leray-Schauder index and the critical group near 0.
Abdel R. El Amrouss, Fouzia Moradi, Mimoun Moussaoui   +2 more
doaj  

Genotyping-by-sequencing provides new genetic and taxonomic insights in the critical group of Centaurea tenorei. [PDF]

Front Plant Sci, 2023
De Luca D, Del Guacchio E, Cennamo P, Paino L, Caputo P.   +4 more
europepmc   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

COMPARISON OF DIFFERENT APPROACHES TO POPULATION EXPOSURE LIMITATION AT RADIOACTIVE CONTAMINATION OF THE ENVIRONMENT (AT THE EXAMPLE OF EXTERNAL EXPOSURE ON TERRITORIES CONTAMINATED AFTER THE CHERNOBYL ACCIDENT)

Радиационная гигиена, 2017
The article is dedicated to comparison of different approaches to population exposure limitation at the example of external exposure of population living on territories contaminated after the accident at Chernobyl NPP.
V. Yu. Golikov
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Existence of three solutions for higher order BVP with parameters via Morse theory

Electronic Journal of Differential Equations, 2016
We prove the existence of at least three solutions to a general Lidstone problem using the Morse Theory.
Mariusz Jurkiewicz, Bogdan Przeradzki
doaj