Results 101 to 110 of about 3,452,336 (316)

The SQUEEZE pilot trial: a trial to determine whether septic shock reversal is quicker in pediatric patients randomized to an early goal directed fluid-sparing strategy vs. usual care

Pilot and Feasibility Studies
Objective The overall objective of our research is to determine in children with septic shock whether the use of a fluid-sparing strategy results in improved clinical outcomes without an increased risk of adverse events compared to usual care.
Melissa J. Parker, Karen Choong, Alison Fox-Robichaud, Patricia C. Liaw, Lehana Thabane, Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group   +5 more
doaj   +1 more source

On the critical group of matrices

, 2010
18 pages, 5 ...
Corrales, Hugo, Valencia, Carlos E.
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Multiple solutions of nonlinear fractional elliptic equations via Morse theory

Electronic Journal of Differential Equations, 2017
This article concerns the existence and multiplicity of weak solutions of the nonlinear fractional elliptic problem. We extend some well known results of semilinear Laplacian equations to the nonlocal fractional setting. Using the variational methods
Wei Qi, Lin Zhao, Xingjie Yan
doaj  

Refining an acute respiratory distress syndrome animal model supported by extracorporeal membrane oxygenator: incorporating clinically relevant mechanical ventilation strategy upon development

Intensive Care Medicine Experimental
Background Acute respiratory distress syndrome (ARDS) requiring veno-venous extracorporeal membrane oxygenation (VV-ECMO) is associated with high mortality.
Keibun Liu, Gabriele Fior, Nchafatso Obonyo, Hideaki Nonaka, Angelo Milani, Gabriella Abbate, Sofia Portatadino, Chiara Palmieri, Shinichi Ijuin, Kei Sato, Silver Heinsar, Sun Kyun Ro, Lucia Gandini, Kota Hoshino, Noriko Sato, Samia Farah, Carmen Ainola, Margaret R. Passmore, Rachana Panduru, Mahe Bouquet, Emily S. Wilson, Kieran Hyslop, Molly-rose McInerney, Cheng Zhang, Caitlin McGrath, Joshua Paech, Jacky Y. Suen, John F. Fraser, Gianluigi Li Bassi   +28 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Existence and multiplicity of solutions for nonlinear equations involving the square root of the Laplacian

Electronic Journal of Differential Equations, 2017
This paper deals with the existence and multiplicity results for fractional problem involving the square root of the Laplacian $A_{1/2}$ in a bounded domain with zero Dirichlet boundary conditions by Morse theory and critical groups for a $C^{1 ...
Yutong Chen, Jiabao Su, Huanhong Yan
doaj  

Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation

Intensive Care Medicine Experimental
Open-lung ventilation during cardiopulmonary bypass (CPB) in patients undergoing heart transplantation (HTx) is a potential strategy to mitigate postoperative acute respiratory distress syndrome (ARDS).
Varun Karnik, Sebastiano Maria Colombo, Leah Rickards, Silver Heinsar, Louise E. See Hoe, Karin Wildi, Margaret R. Passmore, Mahe Bouquet, Kei Sato, Carmen Ainola, Nicole Bartnikowski, Emily S. Wilson, Kieran Hyslop, Kris Skeggs, Nchafatso G. Obonyo, Charles McDonald, Samantha Livingstone, Gabriella Abbate, Andrew Haymet, Jae-Seung Jung, Noriko Sato, Lynnette James, Benjamin Lloyd, Nicole White, Chiara Palmieri, Mark Buckland, Jacky Y. Suen, David C. McGiffin, John F. Fraser, Gianluigi Li Bassi   +29 more
doaj   +1 more source

'Groups' and the Advent of Critical Race Scholarship [PDF]

SSRN Electronic Journal, 2003
This essay reconsiders Owen Fiss's "Groups and the Equal Protection Clause," sometimes described as having instigated critical scholarship in the area of race. It argues that, from a contemporary vantagepoint, the article appears ambivalent in its critical thrust.
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source