Results 181 to 190 of about 3,452,336 (316)

Fostering Critical Consciousness Through Theater of the Oppressed: A Mixed-Methods Study With Gay, Bisexual, Queer, and Transgender Men in Singapore. [PDF]

J Community Psychol
Puvaneyshwaran D, Low AJ, Chong SY, Wee YX, Lee J, Liang P.   +5 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Family or caregiver outcomes after critical illness (FOCUS): a protocol for a core outcome set development study. [PDF]

BMJ Open
Brown C, Hartley P, Malyon A, Connolly B, Lone NI, McPeake J.   +5 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Mindfulness-based cognitive therapy as a psychological strategy for mitigating emotional exhaustion among critical care nurses. [PDF]

J Educ Health Promot
Jazan HF, Mohammed SH.
europepmc   +1 more source

Three scenarios for a critical architecture of desert mobility

, 2007
An invitation to consider the existence of critical architecture has prompted me to present another way of looking at the 'hybrid' architectures that are often encountered in the Australian outback.
Lee, Gini
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Dynamic analysis of critical maternal complications in tertiary hospitals in Wuxi: A study based on four years of monitoring data. [PDF]

PLoS One
Xu Y, Hua P, Shen Y.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Clinical validation of the Rapid Cough Questionnaire across diverse lung diseases. [PDF]

BMJ Open Respir Res
Koo HK, An TJ, Joo H, Rhee CK, Kim YH, Kim SK, Min KH, Kim DK, Shin JW, Yoon HK, Jang SH, Park YB, Kim JW, Moon JY, Korean Cough Study Group in the Korean Academy of Tuberculosis and Respiratory Disease (KATRD).   +14 more
europepmc   +1 more source