Results 281 to 290 of about 24,963,787 (378)

Additional file 1 of Is the incidence of ABO blood groups incompatibility among Egyptian mothers and its relation to critical neonatal hyperbilirubinemia in healthy term and near-term newborns worth screening? Al Galaa Teaching Hospital experience

Makhlouf, Mona Sayed Aly Hassan, Youssif, Mohammed Mourad, Abohleka, Sherif Mohamed Safwat Abdelbaky, Shahine, Marwa Radwan Abbass, Basheer, Hoda Basheer Hussein   +4 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Regional retrospective observational analysis of the impact of enhanced care teams on trauma morbidity and mortality outcomes. [PDF]

Scand J Trauma Resusc Emerg Med
Smith C, McHenry R, Norman S, Hardern R.
europepmc   +1 more source

Critical test of isotropic periodic sum techniques with group-based cut-off schemes

, 2018
Takuma Nozawa, Kenji Yasuoka, Kazuaki Z. Takahashi   +2 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Simulation-Based Bayesian Predictive Probability of Success for Interim Monitoring of Clinical Trials With Competing Event Data: Two Case Studies. [PDF]

Pharm Stat
Micoli C, Crippa A, Connor JT, I‐SPY COVID Consortium, Eklund M, Discacciati A.   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Latent Classes in Long-Term Functional Status in Children With Recurrent Critical Illness. [PDF]

Crit Care Med
Heneghan JA, Velusamy KR, Ramgopal S, Goodman DM, Evans MD, Hallman M, Feldman A, Akande MY.   +7 more
europepmc   +1 more source

Health Status of Particularly Vulnerable Tribal Groups of ITDA KR Puram, India: A Critical Outlook

, 2019
Chinnamanaidu Jammu
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source