Results 51 to 60 of about 24,963,787 (378)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Recovery of organ-specific tissue oxygen delivery at restrictive transfusion thresholds after fluid treatment in ovine haemorrhagic shock

Intensive Care Medicine Experimental, 2022
Background Fluid resuscitation is the standard treatment to restore circulating blood volume and pressure after massive haemorrhage and shock. Packed red blood cells (PRBC) are transfused to restore haemoglobin levels.
Wayne B. Dyer, Gabriela Simonova, Sara Chiaretti, Mahe Bouquet, Rebecca Wellburn, Silver Heinsar, Carmen Ainola, Karin Wildi, Kei Sato, Samantha Livingstone, Jacky Y. Suen, David O. Irving, John-Paul Tung, Gianluigi li Bassi, John F. Fraser   +14 more
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

Morse Thoery of Saddle Point Reduction with Applications

Axioms
In this paper, we demonstrate that when saddle point reduction is applicable, there is a clear relationship between the Morse index and the critical groups before and after the reduction.
Ran Yang, Qin Xing
doaj   +1 more source

Critical groups of group representations

Linear Algebra and its Applications, 2016
8 ...
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Breakdown of the perturbative renormalization group at certain quantum critical points

, 2004
It is shown that the presence of multiple time scales at a quantum critical point can lead to a breakdown of the loop expansion for critical exponents, since coefficients in the expansion diverge.
D. Belitz, J. Zinn-Justin, Jörg Rollbühler, M. E. Fisher, S. Weinberg, S.-K. Ma, T. R. Kirkpatrick   +6 more
core   +1 more source

Mortality and quality of life in the five years after severe sepsis [PDF]

, 2013
Peer reviewedPublisher ...
Cuthbertson, Brian H, Elders, Andrew, Hall, Sally, Mackenzie, Simon J, Mackirdy, Fiona, Maclennan, Graeme, Taylor, Jane, the Scottish Critical Care Trials Group and the Scottish Intensive Care Society Audit Group   +7 more
core   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Extracorporeal Membrane Oxygenation-Induced Hemolysis: An In Vitro Study to Appraise Causative Factors

Membranes, 2021
In vitro hemolysis testing is commonly used to determine hemocompatibility of ExtraCorporeal Membrane Oxygenation (ECMO). However, poor reproducibility remains a challenging problem, due to several unidentified influencing factors.
Chris Hoi Houng Chan, Katrina K. Ki, Meili Zhang, Cooper Asnicar, Hwa Jin Cho, Carmen Ainola, Mahe Bouquet, Silver Heinsar, Jo Philipp Pauls, Gianluigi Li Bassi, Jacky Suen, John F. Fraser   +11 more
doaj   +1 more source