Concept mapping teaching method and nursing education: a systematic review and meta-analysis. [PDF]
BMC Med EducFaraji A +3 more
europepmc +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Cardiovascular effects of hypertonic lactate solutions: acid-base or metabolic cause, or both? [PDF]
Crit CareFreire Jorge PJ +4 more
europepmc +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
The effect of game-based scenario writing on the clinical reasoning of internship nursing students in cardiovascular emergencies and critical care units. [PDF]
BMC Med EducAntikchi M, Heydari S, Bakhshi F.
europepmc +1 more source
Critical Groups and the Lattice of Varieties [PDF]
Proceedings of the American Mathematical Society, 1969 openaire +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Renormalization group and critical behaviour in gravitational collapse
, 1996 Takashi Hara +2 more
openalex +2 more sources
Functional immune profiling of hyper- and hypo-inflammatory subphenotypes of critical illness: a secondary analysis. [PDF]
Front ImmunolHalstead ES +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source