Results 51 to 60 of about 6,342,270 (352)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Existence and Multiplicity of Solutions for Resonant (p,2)-Equations
Advanced Nonlinear Studies, 2018 We consider Dirichlet elliptic equations driven by the sum of a p-Laplacian ...
Papageorgiou Nikolaos S. +2 more
doaj +1 more source
The critical effect of dependency groups on the function of networks
, 2010 Current network models assume one type of links to define the relations between the network entities. However, many real networks can only be correctly described using two different types of relations. Connectivity links that enable the nodes to function
Buldyrev, Sergey V. +2 more
core +2 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Nontrivial solutions for resonance quasilinear elliptic systems
Advances in Nonlinear AnalysisWe establish an Amann-Zehnder-type result for resonance systems of quasilinear elliptic equations with homogeneous Dirichlet boundary conditions, involving nonlinearities growing asymptotically (p,q)\left(p,q)-linear at infinity.
Borgia Natalino +2 more
doaj +1 more source
On the critical pair theory in abelian groups : Beyond Chowla's Theorem
, 2007 We obtain critical pair theorems for subsets S and T of an abelian group such that |S+T| < |S|+|T|+1. We generalize some results of Chowla, Vosper, Kemperman and a more recent result due to Rodseth and one of the authors.Comment: Submitted to ...
A. L. Cauchy +23 more
core +4 more sources
Patient choice in the NHS: How critical are facilities services in influencing patient choice? [PDF]
, 2006 Purpose – From December 2005, patients in the UK needing an operation will be offered a choice of four or five. These could be NHS trusts, foundation trusts, treatment centres, private hospitals or practitioners with a special interest operating within ...
May, D., Miller, L.
core +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
, 2017 We propose an algebraic framework for generalized graph Laplacians which unifies the study of resistor networks, the critical group, and the eigenvalues of the Laplacian and adjacency matrices.
Dana, Will +4 more
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source