Results 161 to 170 of about 16,071,502 (380)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Semi-classical states for a class of quasilinear Schrödinger equations with a parameter

Electronic Research Archive
In this paper, we study the following quasilinear Schrödinger equation with a parameter: $ -\varepsilon^2\Delta u+V(x)u-\varepsilon^2\kappa\beta\Delta(|u|^{2\beta})|u|^{2\beta-2}u = |u|^{q-2}u+|u|^{(2\beta)2^*-2}u $ in $ \mathbb{R}^N $, where $ N ...
Hongjie Xu, Xianyong Yang
doaj   +1 more source

Review for "Specific Commensal Bacterium Critically Regulates Gut Microbiota Osteoimmunomodulatory Actions During Normal Post-Pubertal Skeletal Growth and Maturation"

, 2019

openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Ground state solutions for asymptotically periodic Schrodinger equations with critical growth

Electronic Journal of Differential Equations, 2013
Using the Nehari manifold and the concentration compactness principle, we study the existence of ground state solutions for asymptotically periodic Schrodinger equations with critical growth.
Hui Zhang, Junxiang Xu, Fubao Zhang
doaj  

Erratum: Safety and efficacy of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with critical limb ischemia [PDF]

, 2016
Melina R. Kibbe, A T Hirsch, Farrell O. Mendelsohn, M Davies, H. Pham, Jorge Saucedo, William A. Marston, W-B Pyun, S-K Min, Brian G. Peterson, Anthony J. Comerota, David Choi, Joshua A. Ballard, R A Bartow, Douglas W. Losordo, W Sherman, Vickie R. Driver, Emerson C. Perin   +17 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

On a fractional magnetic Schrödinger equation in $\mathbb{R}$ with exponential critical growth [PDF]

, 2018
Vincenzo Ambrosio
openalex   +1 more source

Identification of critical growth factors for peripheral nerve regeneration. [PDF]

RSC Adv, 2019
Zhang R, Zhang Y, Yi S.
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source