Results 241 to 250 of about 11,870,254 (353)

Global Existence for Reaction-Diffusion Systems with Mass Control and Critical Growth with Respect to the Gradient

, 2001
Nour Eddine Alaa, Ilham Mounir
openalex   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Metabolic reprogramming in melanoma therapy. [PDF]

Cell Death Discov
Shen D, Zhang L, Li S, Tang L.
europepmc   +1 more source

Oncogenes, growth factors, receptor expression and proliferation markers in digestive neuroendocrine tumours. A critical reappraisal

, 2001
Gianfranco Delle Fave, Vito D. Corleto
openalex   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

The Dual Nature of Cellular Senescence: From Aging Signature to Regenerative Catalyst. [PDF]

Research (Wash D C)
Li P, Yang Y, Qin X, Liao J.
europepmc   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Quantitative Method for Monitoring Tumor Evolution During and After Therapy. [PDF]

J Pers Med
Castorina P, Castiglione F, Ferini G, Forte S, Martorana E.   +4 more
europepmc   +1 more source

Critical Role of the HMGI(Y) Proteins in Adipocytic Cell Growth and Differentiation

, 2001
Rosa Marina Melillo, Giovanna Maria Pierantoni, Stefania Scala, Sabrina Battista, Monica Fedele, Antonella Stella, Maria Cristina De Biasio, Gennaro Chiappetta, Vincenzo Fidanza, Gianluigi Condorelli, Massimo Santoro, Carlo M. Croce, Giuseppe Viglietto, Alfredo Fusco   +13 more
openalex   +1 more source

Beyond p‐values: Assessing clinical significance in acupuncture research

Advanced Chinese Medicine, EarlyView.
Abstract In acupuncture randomized controlled trials (RCTs), the proper interpretation of results requires a thorough understanding of key statistical concepts such as p‐value, effect size, and the minimal clinically important difference (MCID). This paper explores the relationships among these metrics and their implications for assessing the clinical ...
Changzhen Gong
wiley   +1 more source