Results 41 to 50 of about 153,489 (223)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Advances in Mechanical Engineering, 2019 A series of experiments were performed to investigate the thermodynamic instabilities that occur during heating of supercritical endothermic hydrocarbon fuel.
Hui Wang, Wansheng Nie, Lingyu Su
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Вестник Донского государственного технического университета, 2018 The experimental comparisons between the critical heat flux values under the unsaturated boiling of water-ethanol and water-isoamyl alcohol binary mixtures, and the external evaporation rates of the corresponding liquid weights are presented.
Viktor V. Romanov
doaj
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
TechnologiesIn the present work, a new analytical model of polytropic flow in constant-diameter pipelines is developed to accurately describe the flow of compressible gases, including natural gas and hydrogen, explicitly accounting for heat exchange between the ...
Laszlo Garbai +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
EngineeringMolten salt is widely adopted in diverse thermal energy storage systems owing to its exceptional thermodynamic properties and economical cost.
Yifan Gui +5 more
doaj +1 more source
Frontiers in Mechanical Engineering, 2017 The use of immiscible liquids for cooling of surfaces with high heat generation density is proposed based on the experimental verification of its superior cooling characteristics in fundamental systems of pool boiling and flow boiling in a tube.
Yasuhisa Shinmoto +3 more
doaj +1 more source