Results 41 to 50 of about 20,381,842 (254)

Australian infrastructure audit [PDF]

, 2015
Examines the drivers of future infrastructure demand, particularly population and economic growth. Summary The Australian Infrastructure Audit takes a strategic approach to assessing our nation\u27s infrastructure needs.
Infrastructure Australia
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

NATIONAL NAVIGATION-COMMUNICATION ECOSYSTEM FOR CRITICAL INFORMATION INFRASTRUCTURE PROTECTION

Безопасность информационных технологий
This paper proposes to implement a domestic Navigation and Communication ecosystem to protect the critical information infrastructure (CII) of the Russian Federation.
Viktor V. Yurov, Zakhar K. Kondrashov, Evgenii I. Starovoitov   +2 more
doaj   +1 more source

Interdependency and Priority of Critical Infrastructure Information (Case Study: Indonesia Payment System)

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2022
The sturdy and reliable payment system is one of the most important systems in the digitalization era, especially in the pandemic COVID-19 period. As part of Critical Infrastructure Information (CII), a strategy to protect the payment system is needed to
Arini Muhafidzah, Kalamullah Ramli
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Critical Information Infrastructure Protection (CIIP):\ud Draft technical Report for the Australian Institute of Criminology [PDF]

, 2006
This chapter aims to examine vulnerability in Australia’s critical infrastructure assets and examine to what extent cyber-criminals or cyber-terrorists are able to manipulate or exploit weaknesses in the protection of these crucial services.
Chantler, Alan N., Broadhurst, Roderic
core  

Conceptual model of information protection of critical information infrastructure objects of Ukraine [PDF]

, 2021
Досліджено проблему вибору моделі захисту інформації на об’єктах критичної інформаційної інфраструктури України. Проведено аналіз сучасних моделей захисту комп’ютерних систем і мереж, що є основою об’єктів критичної інформаційної інфраструктури. Показано,
Максимець, Андрій Володимирович, Гирда, Віра Анатоліївна, Кожедуб, Юлія Василівна, Василенко, Сергій Вікторович   +3 more
core   +1 more source

On the issue of categorization of objects of critical information infrastructure of seaports

Безопасность информационных технологий, 2020
The purpose of the article is to consider the problematic issues that arise during the categorization of CII objects. Seaports are of strategic importance for the development of the Russian Federation's economy and transport support for foreign trade. In
Kristina V. Natashova, Sergey S. Sokolov, Oleg N. Gubernatorov, Anatoliy P. Nyrkov, Anton V. Kirikov   +4 more
doaj   +1 more source