Results 51 to 60 of about 1,566,243 (295)

Commercial critical systems and critical infrastructure protection : a future research agenda [PDF]

open access: yes, 2007
Secure management of Australia’s commercial critical infrastructure presents ongoing challenges to owners and the government. Although it is currently managed through high-level information sharing via collaboration, but does this suit the ...
Leitch, Shona, Warren, Matthew
core   +1 more source

Scaling Laws for Infrastructure Single and Multihop Wireless Networks in Wideband Regimes

open access: yes, 2014
With millimeter wave bands emerging as a strong candidate for 5G cellular networks, next-generation systems may be in a unique position where spectrum is plentiful.
Erkip, Elza   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Role of Chlorides in Corrosion of Reinforcing Steel in Concrete

open access: yesCorrosion and Materials Degradation
Chlorides have long been held responsible for the initiation and progression of the corrosion of reinforcing steels in concrete structures, with higher concentrations assumed to cause earlier and more severe subsequent reinforcement corrosion.
Robert E. Melchers, Igor A. Chaves
doaj   +1 more source

Analytics for Protecting Critical Infrastructure

open access: yesCommunications, 2015
In this paper we review the key trends related to application of information technology and, in particular, automated data analysis to the problem of protecting critical infrastructure.
Adam Zagorecki   +2 more
doaj   +1 more source

Early warning system for the prevention and control of unauthorized accesses to air navigation services infrastructures [PDF]

open access: yes, 2015
Early warning systems are fundamental instruments for the management of critical situations since they are able to signal in advance any anomaly with respect to ordinary situations.
Accettura, Antonella   +5 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

National and European Critical Infrastructure

open access: yesApplied Medical Informatics, 2021
What exactly is the national critical infrastructure? According to the law, we identify several conditions that must be met in terms of the vocation of an element, system or component thereof to be identified as a potential national critical ...
Călin MUNTEAN   +2 more
doaj  

Trends in critical infrastructure protection in Germany [PDF]

open access: yes, 2014
Critical Infrastructures failures cause harmful consequences to the population, because they disrupt the supply of necessary goods and services. The failures pose an indirect threat, as they will regularly be triggered by natural hazards, technical ...
Eismann, Christine
core   +1 more source

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