Results 71 to 80 of about 379,832 (300)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Critical infrastructure protection under imperfect attacker perception
, 2010 This paper considers the problem of allocating finite resources among the elements of a critical infrastructure system in order to protect it from antagonistic attacks.
Jenelius, Erik, +2 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Role of Chlorides in Corrosion of Reinforcing Steel in Concrete
Corrosion and Materials DegradationChlorides have long been held responsible for the initiation and progression of the corrosion of reinforcing steels in concrete structures, with higher concentrations assumed to cause earlier and more severe subsequent reinforcement corrosion.
Robert E. Melchers, Igor A. Chaves
doaj +1 more source
Analytics for Protecting Critical Infrastructure
Communications, 2015 In this paper we review the key trends related to application of information technology and, in particular, automated data analysis to the problem of protecting critical infrastructure.
Adam Zagorecki +2 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Influence of Critical Infrastructure on Enterprise Economic Security
, 2015 This article deals with critical infrastructure and its influence on enterprise economic security. In the introduction, the sectors of critical infrastructure from the point of view of the European Union, Czech Republic and Slovak Republic are ...
David Rehak +2 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
National and European Critical Infrastructure
Applied Medical Informatics, 2021 What exactly is the national critical infrastructure? According to the law, we identify several conditions that must be met in terms of the vocation of an element, system or component thereof to be identified as a potential national critical ...
Călin MUNTEAN +2 more
doaj
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source