Results 81 to 90 of about 379,832 (300)

Determinants of Critical Infrastructure Resources

Foundations of Management, 2017
This article is devoted to the issue of how resources are interpreted in the form of technology reactors that, as a result of unexpected circumstances, turn into pyramidal or avalanche threat dynamics.
Ostrowska Teresa, Krupa Tadeusz
doaj   +1 more source

Identifying critical elements of road infrastructure using cascading impact assessment

Transport, 2020
Road transport is a key means of transporting people and cargo on land. Its particular advantages are speed and operability, which are balanced, however, by dependence on road infrastructure.
David Rehak, David Patrman, Veronika Brabcová, Zdeněk Dvořák   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

The terrorist threat to critical infrastructure from the perspective of criminal risk

Bulletin of "Carol I" National Defense University
The field of critical infrastructure protection emerged as part of the fight against terrorism. Although a transition to an all-hazards approach has taken place, terrorism remains a significant threat to entities providing essential services. The relief
Sorina-Denisa POTCOVARU
doaj   +1 more source

3D sensors in critical infrastructure

MATEC Web of Conferences, 2018
The danger of terrorism is a result of the increased risk of critical infrastructure. We will focus on enumerating each area then listing of possible real uses in security and protection and finally we will focus in the list of used 3D sensors (in ...
Miroslav Marcanik, Michal Sustek, Roman Jasek   +2 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Risk-based analysis of the vulnerability of urban infrastructure to the consequences of climate change

, 2022
5575This chapter gives an introduction to risk-based vulnerability assessment of urban infrastructure regarding the consequences of climate change, by describing an approach developed as part of the EU-funded research and innovation project Climate ...
Ullrich, Oliver, Bogen, Manfred, Worst, Rainer, Abajo, B., Lückerath, Daniel, Dumonteil, M., Bosch, P., Mendizabal, M., Feliu, E., Carter, J., Rome, Erich, Streberová, E., Connelly, A.   +12 more
core   +1 more source

Elektroenergetyczna infrastruktura krytyczna w województwie zachodniopomorskim – 10 lat po blackoucie

Przegląd Zachodniopomorski, 2020
Electricity grids failures, caused by the natural forces, occur often locally and can be handled by the grid’s operator services. If, however, a large number of elements are damaged over a vast area, a large territory is devoid of power supply.
Ewelina Kochanek
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source