Aid and AIDS: a delicate cocktail [PDF]
Development assistance targeting health overwhelmingly concentrates on HIV/AIDS. This column argues that that focus neglects critical demographic issues and degrades health infrastructure, particularly in Sub-Saharan Africa.
Dalen van, H.P., Reuser, M.
core +1 more source
Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization
ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung +190 more
wiley +1 more source
The security implications of geoengineering:blame,imposed agreement and the security of critical infrastructure [PDF]
The prospect of solar geoengineering in response to climate change (on the basis of its supposedly significantly lower cost and/or more rapid impact on global temperature than carbon reduction strategies) raises a number of security concerns that have ...
Cairns, Rose, Nightingale, Paul
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Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Game Theory for Secure Critical Interdependent Gas-Power-Water Infrastructure
A city's critical infrastructure such as gas, water, and power systems, are largely interdependent since they share energy, computing, and communication resources. This, in turn, makes it challenging to endow them with fool-proof security solutions.
Ferdowsi, Aidin +3 more
core +1 more source
Selected Issues Concerning Critical Infrastructure Security Management
Based on the assessment of contemporary reality, it can be said that one of the most critical functions of a modern state is to provide its citizens with an acceptable level of security – that is to say, to create optimal conditions for protection ...
Bogusław Jagusiak, Waldemar Kaczmarek
doaj +1 more source
Planned Adaptation in Design and Testing of Critical Infrastructure: The Case of Flood Safety in The Netherlands [PDF]
In the Netherlands, dykes and other primary water defence works are assets that are essential to keep the society and economy functioning, by protecting against flooding from sea and rivers due to extreme events.
Bloemen, P, Petersen, AC
core

