Results 221 to 230 of about 5,041,885 (292)

Etrinabdione (VCE-004.8), a B55α activator, promotes angiogenesis and arteriogenesis in critical limb ischemia. [PDF]

J Transl Med
García-Martín A, Prados ME, Lastres-Cubillo I, Ponce-Diaz FJ, Cerero L, Garrido-Rodríguez M, Navarrete C, Pineda R, Rodríguez AB, Muñoz I, Moya J, Medeot A, Moreno JA, Chacón A, García-Revillo J, Muñoz E.   +15 more
europepmc   +1 more source

Cerebrovascular flow‐mediated dilation in humans: Methodological challenges, physiological interpretation and future integrations

Experimental Physiology, EarlyView.
Abstract Arterial shear‐mediated vasodilation is a well‐established measure of endothelial function and serves as a critical biomarker for cardiovascular disease risk. Endothelial function can be measured using a variety of experimental methodologies; however, the most widely adopted technique is ultrasound‐based flow‐mediated dilation (FMD), in which ...
Yi Zhen Bao, Tabitha V. Craig, Jenna C. McCrone, Kurt J. Smith, Michael M. Tymko   +4 more
wiley   +1 more source

Corrigendum to 'NIR light-propelled Janus Polydopamine@Mesoporous silica gene delivery nanomotor for the enhanced gene treatment of critical limb ischemia' [Mater. Today Bio, Volume 33, August 2025, 101950 https://doi.org/10.1016/j.mtbio.2025.101950]. [PDF]

Mater Today Bio
Gui L, Wang S, Miao S, Qiao M, Jiao Y, Chen H, Li W, Zou J, Du X.   +8 more
europepmc   +1 more source

Small muscle mass aerobic exercise in health and disease: Unique insights into muscle vascular and metabolic control and performance

Experimental Physiology, EarlyView.
Abstract Studies of small muscle mass exercise (SMME) have revealed that the peripheral O2 transport–utilization cascade is a dynamically regulated system in which perfusive and diffusive components can be selectively amplified, redistributed and mechanically limited depending on contraction pattern, recruitment strategy and intramuscular pressure ...
Shunsaku Koga, David C. Poole, Thomas J. Barstow, Dai Okushima, Richie P. Goulding   +4 more
wiley   +1 more source

Histological Changes in the Popliteal Artery Wall in Patients with Critical Limb Ischemia. [PDF]

Diagnostics (Basel)
Andercou O, Andrei MC, Gheban D, Marian D, Coman HF, Oprea VA, Mihaileanu FV, Ciocan R, Cucuruz B, Stancu B.   +9 more
europepmc   +1 more source

Mechanical pressure on endothelial cells mediates remote ischaemic preconditioning‐induced neuroprotection via miR‐126

Experimental Physiology, EarlyView.
Abstract Remote ischaemic preconditioning (RIPC) uses brief limb ischaemia to protect distant organs, but the mechanism of travel of the protective signal remains unclear. This study investigated whether endothelial cells (ECs) contribute to RIPC‐induced neuroprotection and the underlying mechanisms.
Xiaojie Wang, Lei Yan, Hongwei Zhu, Yifan Li, Qi Liu, Wei Li, Kerui Gong, Zhijun Zhao, Chunyang Zhang, Gang Fu, Guo Shao, Xunming Ji   +11 more
wiley   +1 more source

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

The Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray, Girish Halemirle, Beatriz Ferrán, Hadyn Rose, Traci L. Redwine, Sophia Pham, Bo Hagy, Atul Pranay, Jennifer Giorgione, Stacy A. Hussong, Veronica Galvan, Kenneth Humphries, Holly Van Remmen, Mike Kinter, William E. Sonntag, Pankaj K. Singh, Carlos Manlio Díaz‐García   +16 more
wiley   +1 more source

Correction: Intentional coronary revascularization versus conservative therapy in patients after peripheral artery revascularization due to critical limb ischemia: the INCORPORATE trial. [PDF]

Clin Res Cardiol
Toth GG, Brodmann M, Kanoun Schnur SS, Bartus S, Vrsalovic M, Krestianinov O, Kala P, Bil J, Gil R, Kanovsky J, Di Serafino L, Paolucci L, Barbato E, Mangiacapra F, Ruzsa Z.   +14 more
europepmc   +1 more source

Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints

The Journal of Physiology, EarlyView.
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero, Franck Brocherie, Olivier Girard, Nathan Townsend, Chris J. McNeil, Grégoire P. Millet   +5 more
wiley   +1 more source

Investigational New Drug-enabling studies to use genetically modified mesenchymal stromal cells in patients with critical limb ischemia. [PDF]

Stem Cells Transl Med
Cressman A, Le B, Morales D, Yen WS, Wu FJ, Perotti NH, Fury B, Nolta JA, Fierro FA.   +8 more
europepmc   +1 more source