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A micro-fragmented collagen gel as a cell-assembling platform for critical limb ischemia repair. [PDF]

open access: yesBioact Mater
Chung H   +9 more
europepmc   +1 more source

Critical limb ischemia

Internal and Emergency Medicine, 2011
Critical limb ischemia (CLI) represents the most advanced clinical stage of peripheral arterial disease. It is usually caused by obstructive atherosclerotic arterial disease and is associated with very high morbidity and mortality. The pathophysiology of CLI is a complex and chronic process affecting the macrovascular and microvascular circulation of ...
GRESELE, Paolo   +2 more
openaire   +4 more sources

Critical limb ischemia

Current Treatment Options in Cardiovascular Medicine, 2001
Patients with critical limb ischemia (CLI) present with ischemic rest pain or with tissue loss. Tissue loss, in its mildest presentation, includes focal ischemic ulceration or nonhealing wounds. Gangrene is the manifestation of severe chronic ischemia.
David L., Dawson, Ryan T., Hagino
openaire   +3 more sources

Critical limb ischemia

Current Treatment Options in Cardiovascular Medicine, 2007
Critical limb ischemia (CLI) is the most severe manifestation of peripheral artery disease (PAD). Without timely recognition, appropriate diagnosis, and revascularization, patients with CLI are at risk for amputation or potentially fatal complications.
David L, Dawson, Joseph L, Mills
openaire   +2 more sources

Critical Limb Ischemia

Surgical Clinics of North America, 2013
Critical limb ischemia refers to the clinical state of advanced arterial occlusive disease, placing an extremity at risk for gangrene and limb loss. Critical limb ischemia has 2 broad clinical subcategories that are vital to differentiate: acute limb ischemia and chronic arterial occlusive disease.
exaly   +3 more sources

Critical Limb Ischemia

Annals of Vascular Surgery, 2000
Critical limb ischemia (CLI) is defined as a condition that endangers all or part of the limb if no radical improvement in blood flow can be achieved by means of surgery, interventional radiology, or medical treatment163 (Figure 42.1).
Leonella Pasqualini, Elmo Mannarino
openaire   +2 more sources

Critical and Acute Limb Ischemia

Angiology, 2012
Some patients with peripheral arterial disease may present with critical limb ischemia, a condition associated with high rates of morbidity and mortality. Early diagnosis and effective medical therapy and revascularization are indicated to avoid amputation and reduce mortality.
Nezar, Falluji, Debabrata, Mukherjee
openaire   +2 more sources

Critical Limb Ischemia

2009
At the beginning of the third millennium the studies on the epidemiology of cardiovascular diseases (CVD) led to the conclusion that we are facing a very serious public health threat, that of a pandemic of cardiovascular disease. In this context, peripheral arterial disease (PAD) and its components [i.e., intermittent claudication (IC), critical limb ...
David E. Allie   +4 more
openaire   +1 more source

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