Results 261 to 270 of about 107,923 (299)
Some of the next articles are maybe not open access.
2009
At the beginning of the third millennium the studies on the epidemiology of cardiovascular diseases (CVD) led to the conclusion that we are facing a very serious public health threat, that of a pandemic of cardiovascular disease. In this context, peripheral arterial disease (PAD) and its components [i.e., intermittent claudication (IC), critical limb ...
David E. Allie +4 more
openaire +1 more source
At the beginning of the third millennium the studies on the epidemiology of cardiovascular diseases (CVD) led to the conclusion that we are facing a very serious public health threat, that of a pandemic of cardiovascular disease. In this context, peripheral arterial disease (PAD) and its components [i.e., intermittent claudication (IC), critical limb ...
David E. Allie +4 more
openaire +1 more source
Critical Limb Ischemia: Endovascular Strategies for Limb Salvage
Progress in Cardiovascular Diseases, 2011Critical limb ischemia (CLI) represents the most severe clinical manifestation of peripheral arterial disease, defined as the presence of chronic ischemic rest pain, ulcers, or gangrene attributable to objectively proven arterial occlusive disease. The dominant pathology underlying CLI is atherosclerosis, distributed at multiple levels along the length
Philip B, Dattilo, Ivan P, Casserly
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2014
Critical limb ischemia (CLI) represents the most severe manifestation of peripheral arterial disease and is defined as the presence of chronic ischemic rest pain, ischemic ulcers, or gangrene attributable to objectively proven arterial occlusive disease.
Michael A. Golden, Brant W. Ullery
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Critical limb ischemia (CLI) represents the most severe manifestation of peripheral arterial disease and is defined as the presence of chronic ischemic rest pain, ischemic ulcers, or gangrene attributable to objectively proven arterial occlusive disease.
Michael A. Golden, Brant W. Ullery
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Journal of Controlled Release, 2019
Synthetic chemically modified mRNAs (modRNA) encoding vascular endothelial growth factor (VEGF) represents an alternative to gene therapy for the treatment of ischemic cardiovascular injuries.
Ziyou Yu +15 more
semanticscholar +1 more source
Synthetic chemically modified mRNAs (modRNA) encoding vascular endothelial growth factor (VEGF) represents an alternative to gene therapy for the treatment of ischemic cardiovascular injuries.
Ziyou Yu +15 more
semanticscholar +1 more source
Critical and Acute Limb Ischemia
Angiology, 2012Some patients with peripheral arterial disease may present with critical limb ischemia, a condition associated with high rates of morbidity and mortality. Early diagnosis and effective medical therapy and revascularization are indicated to avoid amputation and reduce mortality.
Nezar, Falluji, Debabrata, Mukherjee
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Management of chronic critical limb ischemia
Cardiology Clinics, 2002The patient with CLI is challenging and requires a multi-disciplinary approach to effective management that involves a team of individuals proficient in various aspects of vascular disease. Fig. 4 details the approach at the University of Michigan's comprehensive vascular medicine program.
Sanjay, Rajagopalan, P Michael, Grossman
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Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2008
Critical limb ischemia can be divided into acute and chronic forms. All patients suspected of the acute form should be evaluated immediately, as urgent revascularization is usually necessary. Chronic critical limb ischemia is the most complicated type of peripheral artery disease (PAD). Typical for it are pain at rest and necrosis or gangrene. The most
C, Denzel, W, Lang
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Critical limb ischemia can be divided into acute and chronic forms. All patients suspected of the acute form should be evaluated immediately, as urgent revascularization is usually necessary. Chronic critical limb ischemia is the most complicated type of peripheral artery disease (PAD). Typical for it are pain at rest and necrosis or gangrene. The most
C, Denzel, W, Lang
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Matrix Metalloproteinases in Critical Limb Ischemia
Journal of Surgical Research, 2008Critical limb ischemia (CLI) is most commonly the result of arterial occlusive disease, specifically atherosclerotic plaque formation and rupture within the infrainguinal arteries. The physiological response to CLI is partial limb reperfusion via the distinct processes of angiogenesis and arteriogenesis.
Mark J, Hobeika +4 more
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Endovascular therapy for critical limb ischemia
Expert Review of Cardiovascular Therapy, 2015Critical limb ischemia (CLI) represents an advanced disease state of peripheral arterial disease. It manifests as lower extremity ischemic rest pain or ischemic skin lesions leading to ulceration or gangrene. Patients with CLI often have multiple medical comorbidities and a 1-year mortality rate of 25% and a 1-year amputation rate of 25%. Historically,
Arturo, Dominguez +4 more
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Impact of Frailty on Clinical Outcomes in Patients With Critical Limb Ischemia
Circulation. Cardiovascular Interventions, 2018Background: The predictive ability of patient frailty on clinical outcomes after revascularization in patients with critical limb ischemia remains largely unknown.
Yasuaki Takeji +9 more
semanticscholar +1 more source