Results 291 to 300 of about 76,569 (361)

Cannabidiol attenuates epileptic phenotype and increases survival in a mouse model of developmental and epileptic encephalopathy type 1

open access: yesEpilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathy type 1 (DEE1) is a rare drug‐resistant pediatric epilepsy caused by trinucleotide repeat expansions in the X‐linked ARX gene, leading to elongation of the first polyalanine tract. It presents with early onset tonic seizures or spasms, developmental and cognition delay, and high risk of ...
Lucia Verrillo   +9 more
wiley   +1 more source

2. Angiogenic Therapy for Critical Limb Ischemia

open access: bronze, 2008
Yusuke Nakagawa   +4 more
openalex   +2 more sources

WONOEP XVII appraisal: Targeting network excitability beyond the synapse ‐Neurotransmitter, ionic, and electro ‐diffusions

open access: yesEpilepsia, EarlyView.
Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Vincent Magloire   +9 more
wiley   +1 more source

Intentional coronary revascularization versus conservative therapy in patients after peripheral artery revascularization due to critical limb ischemia: the INCORPORATE trial. [PDF]

open access: yesClin Res Cardiol
Toth GG   +14 more
europepmc   +1 more source

The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review

open access: yesEpilepsia, EarlyView.
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu   +2 more
wiley   +1 more source

Considerations and challenges of septic arthritis and osteomyelitis

open access: yesEquine Veterinary Education, EarlyView.
Summary Septic arthritis remains a common orthopaedic condition in both human and veterinary medicine which can cause serious morbidity and pose considerable challenges for clinical management. The majority of the published clinical research in humans and veterinary species has been focused on the diagnosis, treatment, prevention and outcome of this ...
J. B. Engiles, H. L. Stewart
wiley   +1 more source

Patient Agitation in the Intensive Care Unit: A Concept Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim Exploring the concept of patient agitation in the intensive care unit. Background Patient agitation in the intensive care unit is of widespread concern and linked to negative outcomes for patients, staff, and family members. There is currently no consensus on what constitutes agitation in the intensive care context, hindering effective and
Anne Mette N. Adams   +7 more
wiley   +1 more source

A micro-fragmented collagen gel as a cell-assembling platform for critical limb ischemia repair. [PDF]

open access: yesBioact Mater
Chung H   +9 more
europepmc   +1 more source

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