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Surgical Management of Critical Limb Ischemia

Techniques in Vascular and Interventional Radiology, 2005
At the present time, infrainguinal bypass using autogenous vein is the most effective and durable treatment for chronic limb ischemia caused by long-segment, diffuse, atherosclerotic occlusive disease. Quality of the vein conduit is the most important factor that determines operative success.
Jeffrey L. Ballard, Joseph L. Mills
openaire   +3 more sources

Endovascular therapy for critical limb ischemia

Vascular Medicine, 2008
Abstract Chronic critical limb ischemia (CLI) occurs when arterial perfusion is reduced below a threshold level that results in rest pain and/or tissue breakdown in the lower extremities. Importantly, it is associated with high cardiovascular morbidity and mortality. Without prompt revascularization, CLI may result in loss of a limb (i.e. amputation)
Arain, Salman A., White, Christopher J.
openaire   +4 more sources

Treatment of critical limb ischemia in the elderly

Archives of Gerontology and Geriatrics, 1996
Acute critical limb ischemia (CLI) is a rather frequent clinical event in elderly patients. Atherosclerotic plaques or cardiopathies (atrial enlargement and fibrillation, ventricular thrombosis) are the most frequent clinical situations related to peripheral embolization.
S. Forconi, M. Cuerrini
openaire   +3 more sources

Vascular access in critical limb ischemia

Cardiovascular Revascularization Medicine, 2016
Currently, percutaneous endovascular intervention is considered a first line of therapy for treating patients with critical limb ischemia. As the result of remarkable development of techniques and technologies, percutaneous endovascular intervention has led to rates of limb salvage comparable to those achieved with bypass surgery, with fewer ...
Won Yu Kang   +13 more
openaire   +2 more sources

Chronic Critical Limb Ischemia

2006
A 74 year-old male with a history of diabetes, hypertension, hypercholesterolaemia, coronary artery bypass and active tobacco use presented with a gangrenous right first toe. The patient stated that he had no history of trauma to the area, and complained of rest pain in the foot.
Anil Hingorani, Enrico Ascher
openaire   +2 more sources

Therapeutic angiogenesis for critical limb ischemia

Seminars in Vascular Surgery, 2014
The application of gene- and cell-based therapies to promote angiogenesis is a novel concept to treat lower-limb critical limb ischemia (CLI) and may provide an unmet need for patients with no options for revascularization. Proof of concept was demonstrated in animal models resulting in clinical trials that have confirmed the feasibility and short-term
Dennis F. Bandyk, Sae Hee Ko
openaire   +3 more sources

Actovegin in treatment of critical limb ischemia

Khirurgiya. Zhurnal im. N.I. Pirogova, 2015
The problem of distal occlusion of the lower limbs cannot be currently considered solved due to too large number (40%) of postoperative amputations. Only surgical way of disease management seems impossible. Thus multidisciplinary approach is necessary.To determine the effectiveness of actovegin in treatment of critical ischemia of lower extremities.The
D. R Pershakov, Fomin Aa
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Building a Critical Limb Ischemia Program

Current Treatment Options in Cardiovascular Medicine, 2016
The need to develop highly qualified, multidisciplinary critical limb ischemia (CLI) programs has gained significant momentum. Due to the systemic nature of the disease, patients with CLI are inherently medically complex and often present with multiple comorbidities.
Mitchell D. Weinberg   +4 more
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Thrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion

Signal Transduction and Targeted Therapy, 2022
Yang Shu, Yu-Jie Guo, Scott Ayton
exaly  

Pedal Access in Critical Limb Ischemia

2013
Critical limb ischemia (CLI) commonly involves popliteal and infrapopliteal arterial occlusions. Surgical revascularization may be limited by poor distal targets, lack of autologous vein, and co morbid conditions. Endovascular therapy may be an option even in this group of patients with no surgical options, but is limited by the need to first cross ...
openaire   +3 more sources

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