Results 361 to 370 of about 129,036 (402)

Management of chronic critical limb ischemia

Cardiology Clinics, 2002
The patient with CLI is challenging and requires a multi-disciplinary approach to effective management that involves a team of individuals proficient in various aspects of vascular disease. Fig. 4 details the approach at the University of Michigan's comprehensive vascular medicine program.
P. Michael Grossman, Sanjay Rajagopalan
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Endovascular therapy for critical limb ischemia

Expert Review of Cardiovascular Therapy, 2015
Critical limb ischemia (CLI) represents an advanced disease state of peripheral arterial disease. It manifests as lower extremity ischemic rest pain or ischemic skin lesions leading to ulceration or gangrene. Patients with CLI often have multiple medical comorbidities and a 1-year mortality rate of 25% and a 1-year amputation rate of 25%. Historically,
Arturo Dominguez, Mitul Patel, Ehtisham Mahmud, John Bahadorani, Ryan Reeves   +4 more
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Matrix Metalloproteinases in Critical Limb Ischemia

Journal of Surgical Research, 2008
Critical limb ischemia (CLI) is most commonly the result of arterial occlusive disease, specifically atherosclerotic plaque formation and rupture within the infrainguinal arteries. The physiological response to CLI is partial limb reperfusion via the distinct processes of angiogenesis and arteriogenesis.
Rachel S. Edlin, Bart E. Muhs, Mark J. Hobeika, Paul J. Gagne, Mikel Sadek   +4 more
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Surgical Management of Critical Limb Ischemia

Techniques in Vascular and Interventional Radiology, 2005
At the present time, infrainguinal bypass using autogenous vein is the most effective and durable treatment for chronic limb ischemia caused by long-segment, diffuse, atherosclerotic occlusive disease. Quality of the vein conduit is the most important factor that determines operative success.
Jeffrey L. Ballard, Joseph L. Mills
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Impact of Frailty on Clinical Outcomes in Patients With Critical Limb Ischemia

Circulation. Cardiovascular Interventions, 2018
Background: The predictive ability of patient frailty on clinical outcomes after revascularization in patients with critical limb ischemia remains largely unknown.
Yasuaki Takeji, K. Yamaji, Yusuke Tomoi, J. Okazaki, Kiyoshi Tanaka, Ayumu Nagae, H. Jinnouchi, S. Hiramori, Y. Soga, K. Ando   +9 more
semanticscholar   +1 more source

Endovascular therapy for critical limb ischemia

Vascular Medicine, 2008
Abstract Chronic critical limb ischemia (CLI) occurs when arterial perfusion is reduced below a threshold level that results in rest pain and/or tissue breakdown in the lower extremities. Importantly, it is associated with high cardiovascular morbidity and mortality. Without prompt revascularization, CLI may result in loss of a limb (i.e. amputation)
Arain, Salman A., White, Christopher J.
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Treatment of critical limb ischemia in the elderly

Archives of Gerontology and Geriatrics, 1996
Acute critical limb ischemia (CLI) is a rather frequent clinical event in elderly patients. Atherosclerotic plaques or cardiopathies (atrial enlargement and fibrillation, ventricular thrombosis) are the most frequent clinical situations related to peripheral embolization.
S. Forconi, M. Cuerrini
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Therapeutic angiogenesis for critical limb ischemia

Seminars in Vascular Surgery, 2014
The application of gene- and cell-based therapies to promote angiogenesis is a novel concept to treat lower-limb critical limb ischemia (CLI) and may provide an unmet need for patients with no options for revascularization. Proof of concept was demonstrated in animal models resulting in clinical trials that have confirmed the feasibility and short-term
Dennis F. Bandyk, Sae Hee Ko
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Interim Results of the PROMISE I Trial to Investigate the LimFlow System of Percutaneous Deep Vein Arterialization for the Treatment of Critical Limb Ischemia.

The Journal of invasive cardiology, 2019
OBJECTIVE To investigate the feasibility, safety, and effectiveness of the LimFlow stent-graft system in performing percutaneous deep vein arterialization (pDVA) for treatment of critical limb ischemia (CLI) patients ineligible for conventional ...
J. Mustapha, F. Saab, D. Clair, P. Schneider   +3 more
semanticscholar   +1 more source

Vascular access in critical limb ischemia

Cardiovascular Revascularization Medicine, 2016
Currently, percutaneous endovascular intervention is considered a first line of therapy for treating patients with critical limb ischemia. As the result of remarkable development of techniques and technologies, percutaneous endovascular intervention has led to rates of limb salvage comparable to those achieved with bypass surgery, with fewer ...
Won Yu Kang, Hideaki Ota, Michael J. Lipinski, Nelson L. Bernardo, Ricardo O. Escarcega, Romain Didier, Ron Waksman, Nevin C. Baker, Smita I. Negi, Edward Koifman, Sarkis Kiramijyan, Umberto Campia, Rebecca Torguson, Marco A. Magalhaes   +13 more
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