Results 231 to 240 of about 6,595,830 (298)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Achieving upper-branch steady-state solutions for inerter-damped cable parametric vibration via targeted runge-kutta initial conditions. [PDF]

Sci Rep
Guo Z, Xu S, Tang X, Yao G.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Competency gaps in respiratory therapy: evidence from a global survey. [PDF]

Korean J Med Educ
Skariah TA, Rao UK, Karthika M.
europepmc   +1 more source

Reply to comments on thoracic segmental spinal anaesthesia for Scapular fracture. [PDF]

Indian J Anaesth
Dharamkhele SA, Nasre AH, Rathi MM, Gollapalli VK.   +3 more
europepmc   +1 more source

Correlation between lung ultrasound B lines and clinical as well as echocardiographic parameters in patients on maintenance hemodialysis. [PDF]

Sci Rep
Shah MK, Patel RD, Patel RJ, Mannari JG, Makwana M, Kute V, Ganjiwale J.   +6 more
europepmc   +1 more source