Results 231 to 240 of about 6,661,624 (342)

Systematic review, meta-analysis, and meta-regression of the association of serial leukocyte counts in critically ill patients and mortality. [PDF]

Ann Intensive Care
Arulkumaran N, Dewar F, Ambler G, Arias Lopez MDP, Dos Santos C, De Waele JJ, Lipman J, Paiva JA, Timsit JF.   +8 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

The Arithmetic Operator and the Critical Line: Structural Connections to Spectral Triples, Pair Correlation, and Quantum Phase Transitions

Mennillo, Antonio
openalex   +1 more source

Orbital-effect-induced finite-momentum pairing and Josephson vortex lattice melting in layered Ising superconductors. [PDF]

Natl Sci Rev
Yan H, Liu H, Liu Y, Zhang D, Xie X.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Tandem extracorporeal blood purification therapies for sepsis and acute kidney injury in critically ill children: a state-of-the-art review. [PDF]

Ren Fail
Shirode P, Sethi SK, Nascimento D, Tanna S, Johnson E, Safadi K, Beck T, Bakkaloglu SA, Kirpalani A, Raimer P, Moritz ML, Raina R.   +11 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Advancing emergency airway management: Video laryngoscope <i>vs</i> intubating laryngeal mask airway in critical care. [PDF]

World J Crit Care Med
Feyissa GD.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

The role of age in choosing high-efficacy treatment for multiple sclerosis: an Austrian MS Database study. [PDF]

J Neurol
Hegen H, Föttinger F, Walde J, Berek K, Martinez-Serrat M, Damulina A, Krajnc N, Ponleitner M, Di Pauli F, Enzinger C, Deisenhammer F, Berger T, Khalil M, Bsteh G, Austrian Multiple Sclerosis Database Study group.   +14 more
europepmc   +1 more source