Results 31 to 40 of about 15,954,263 (302)

Fuzzy Critical Path Method Based on Lexicographic Ordering

open access: yes, 2012
The Critical Path Method (CPM) is useful for planning and control of complex projects. The CPM identifies the critical activities in the critical path of an activity network.
Nowpada, Ravi Shankar   +1 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Application of Critical Path Method and Fuzzy Logic in Optimizing Bottled Drinking Water Production

open access: yesInPrime, 2021
Project management is one of the analytical techniques used for planning, scheduling, and making decisions about activities. This is useful so that the project can be implemented optimally and efficiently. Project management can be done by optimizing the
Wanda Wira Yudiarti, Faiz Ainur Razi
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Reasons of delays in construction projects

open access: yesИнженерно-строительный журнал, 2017
Usually, the actual duration of construction projects significantly exceeds the scheduled duration. Reasons for this phenomenon are presented. Firstly, numerous stochastic factors impact on the works.
Yuri Kalugin
doaj   +1 more source

Analysis of Critical Activity in the Hydromechanical Component Fabrication Project for Dam “X” using the Critical Path Method

open access: yesOPSI, 2023
One of the projects currently being undertaken by PT. XYZ is Dam “X”. Based on project management data obtained from PT. XYZ, the actual project construction process experienced a significant delay from the planned schedule, with a delay duration of ...
Pramudi Arsiwi   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

METHODS AND TECHNIQUES REGARDING THE GENERAL TECHNICAL-ECONOMIC IMPROVEMENT OF THE PLANTS [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2013
The capacity of continuous modernisation of our agriculture, in order to obtain some high vegetal and animal productions is reflected first of all by the effects of applying some productions technologies that are as adequate as possible to the natural ...
Georgiana CRUDU
doaj  

Application of Fuzzy theory to project scheduling with critical path method

open access: yesJournal of Applied Sciences and Environmental Management, 2013
In this paper, we analyze the project scheduling problem using fuzzy theory. The crisp activity durations are modeled as triangular fuzzy sets. Fuzzy forward pass was carried out to determine fuzzy activity earliest start, fuzzy event earliest time and ...
MH Oladeinde, DO Itsisor
doaj   +3 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

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