Results 21 to 30 of about 272,357 (265)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Analisis Manajemen Konstruksi Jembatan Kenet Bantul Daerah Istimewa Yogyakarta
Jurnal Civil Engineering Study, 2023 Manajemen konstruksi adalah studi dan praktik manajemen dan aspek teknis industri konstruksi. Manajemen konstruksi juga dapat diartikan sebagai modal komersial yang dilakukan oleh konsultan konstruksi dalam memberi nasihat dan membantu dalam proyek ...
Ohan Farhan
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Application of Critical Path Method and Fuzzy Logic in Optimizing Bottled Drinking Water Production
InPrime, 2021 Project management is one of the analytical techniques used for planning, scheduling, and making decisions about activities. This is useful so that the project can be implemented optimally and efficiently. Project management can be done by optimizing the
Wanda Wira Yudiarti, Faiz Ainur Razi
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Reasons of delays in construction projects
Инженерно-строительный журнал, 2017 Usually, the actual duration of construction projects significantly exceeds the scheduled duration. Reasons for this phenomenon are presented. Firstly, numerous stochastic factors impact on the works.
Yuri Kalugin
doaj +1 more source
OPSI, 2023 One of the projects currently being undertaken by PT. XYZ is Dam “X”. Based on project management data obtained from PT. XYZ, the actual project construction process experienced a significant delay from the planned schedule, with a delay duration of ...
Pramudi Arsiwi +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source