Results 151 to 160 of about 2,672,882 (329)

Profile of cases and factors associated with poor outcomes among patients admitted to the intensive care unit at a regional referral hospital in Bhutan: an observational study

BMC Health Services Research
Introduction Timely admission and treatment of critically ill patients to Intensive Care Units (ICU) is shown to reduce premature mortality. However, low- and middle-income countries face many challenges in providing ICU services.
Thinley Dorji, Sangay Wangmo, Sangay Tenzin, Tenzin Choden, Lok Bahadur Ghalley, Sangay Wangchuk, Choeda Gyaltshen, Kesang Namgyal   +7 more
doaj   +1 more source

Potential and critical pathways of CO2 emissions reduction: A city-based study

Carbon Capture Science & Technology
China has put forward the ''Dual Carbon'' target, carbon peak by 2030 and carbon neutrality by 2060. It is necessary to study the current situation of carbon emissions, carbon reduction potential, and decarbonization paths of industrial cities in China ...
Yangdi Zhou, Zhongquan Liu, Cong Luo, Ziqiang Han, Donglong Lai, Fan Wu, Xiaoshan Li, Liqi Zhang   +7 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Additional file 2 of Critical metabolic pathways and genes cooperate for epoxy fatty acid-enriched oil production in developing seeds of Vernonia galamensis, an industrial oleaginous plant

, 2022
Yan Sun, Baoling Liu, Jinai Xue, Xiaodan Wang, Hongli Cui, Runzhi Li, Xiaoyun Jia   +6 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Transient visual pathway critical for normal development of primate grasping behavior [PDF]

, 2018
Iñaki-Carril Mundiñano, Dylan M. Fox, William C. Kwan, Diego Vidaurre, Leon Teo, Jihane Homman‐Ludiye, Melvyn A. Goodale, David A. Leopold, James A. Bourne   +8 more
openalex   +1 more source

Additional file 4 of RNA-seq analysis reveals the critical role of the novel lncRNA BIANCR in intramuscular adipogenesis through the ERK1/2 signaling pathway

, 2023
Xinhao Ma, Xinran Yang, Dianqi Zhang, Wenzhen Zhang, Xiaoyu Wang, Kuncheng Xie, Jie He, Chugang Mei, Linsen Zan   +8 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Speech-language-hearing instruments to assess peripheral facial palsy: an integrative literature review

Revista CEFAC
Purpose: to describe and analyze the clinical instruments that assess peripheral facial palsy through an integrative literature review. Methods: the precepts for this type of review were followed: research question, identification, selection of studies,
Mariane Maião Pereira, Esther Mandelbaum Gonçalves Bianchini, Mabile Francine Ferreira Silva, Ruth Ramalho Ruivo Palladino   +3 more
doaj   +2 more sources

The tryptophan catabolite or kynurenine pathway in COVID-19 and critical COVID-19: a systematic review and meta-analysis [PDF]

, 2022
Abbas F. Almulla, Thitiporn Supasitthumrong, Chavit Tunvirachaisakul, Ali Abbas Abo Algon, Hussein Kadhem Al‐Hakeim, Michaël Maes   +5 more
openalex   +1 more source