Results 101 to 110 of about 1,732,571 (284)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Critical Exponents and Universality for Fractal Time Processes above the Upper Critical Dimensionality

open access: yesFractal and Fractional
We study the critical behaviors of systems undergoing fractal time processes above the upper critical dimension. We derive a set of novel critical exponents, irrespective of the order of the fractional time derivative or the particular form of ...
Shaolong Zeng   +3 more
doaj   +1 more source

Critical Phenomena in Plasma Membrane Organization and Function. [PDF]

open access: yesAnnu Rev Phys Chem, 2021
Shaw TR, Ghosh S, Veatch SL.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Scale‐free Spatio‐temporal Correlations in Conformational Fluctuations of Intrinsically Disordered Proteins

open access: yesAdvanced Science
The self‐assembly of intrinsically disordered proteins (IDPs) into condensed phases and the formation of membrane‐less organelles (MLOs) can be considered as the phenomenon of collective behavior.
Haoyu Song   +6 more
doaj   +1 more source

Does hardcore interaction change absorbing type critical phenomena?

open access: yes, 2000
It has been generally believed that hardcore interaction is irrelevant to absorbing type critical phenomena because the particle density is so low near an absorbing phase transition.
A. Vespignani   +31 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Boundary Critical Phenomena in SU(3) "Spin" Chains

open access: yes, 2000
SU(3)-invariant "spin" chains with a single impurity, such as a modified exchange coupling on one link, are analyzed using boundary conformal field theory techniques. These chains are equivalent to a special case of the "tJV" model, i.e.
Affleck I   +10 more
core   +2 more sources

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

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