Results 111 to 120 of about 5,376,768 (285)

FATIGUE LIFE PREDICTION METHODOLOGY BASED ON WEIGHT-AVERAGED MAXIMUM SHEAR STRESS PLANE UNDER MULTIAXIAL LOADING

open access: yesJixie qiangdu, 2021
A fatigue life prediction methodology is proposed based on weight-averaged maximum shear stress range plane.Firstly,based on modified Wang and Brown’s reversal counting method,a new approach to the determination of the critical plane is proposed under ...
TAO ZhiQiang   +5 more
doaj  

The mean field equation with critical parameter in a plane domain

open access: yesDifferential and Integral Equations, 2006
13 pages, to appear in Differential and Integral ...
openaire   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

[News Clip: Plane Crash]

open access: yes, 1959
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about a plane crash that occurred.
WBAP-TV (Television station : Fort Worth, Tex.)
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Study of Thickness Effect on Fracture Toughness of High Grade Pipeline Steel

open access: yesMATEC Web of Conferences, 2016
The critical fracture toughness decreases when thickness of specimens increases and stress-strain field in crack tip start changing to plane strain state from plane stress state. In this paper, fracture toughness tests were carried. Based on the analysis
Zhang Hua   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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