Results 181 to 190 of about 1,093,244 (310)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

In Situ Imaging Reveals Efficient Charge Separation in Monolayer MoS₂-WS₂ Type-II Heterojunctions. [PDF]

J Am Chem Soc
Huang Q, Wang Z, Liu R, Yao H, Ni C, Bo T, Wu S, Sun F, Fan F, Mirkin MV.   +9 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Multiaxial fatigue life evaluation using strain energy-based critical plane approach

, 2019
Meng-Fei Hao, Shun‐Peng Zhu, Fu-Long Xia   +2 more
openalex   +1 more source

Gallstone Ileus Secondary to Cholecystoduodenal Fistula: A Case Report and Review of Surgical Management. [PDF]

Case Rep Surg
Adeyemi O, Patel M, Shamoun E, Cort C, Franco C.   +4 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Comparison of Equivalent Stress Methods with Critical Plane Approaches for Multiaxial High Cycle Fatigue Assessment

, 2017
Zafer Engin, Demirkan Çöker
openalex   +1 more source

Cavernous Sinus Cavernous Angioma Presenting As Painful Ophthalmoplegia: Report of a Rare Case Involving the Skull Base. [PDF]

Cureus
Furlan Silva Fabri R, De Melo Rodrigues RM, Soundararajan A.   +2 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Pituitary neuroendocrine tumor with transsellar anastomosis concomitant with internal carotid artery agenesis: illustrative case. [PDF]

J Neurosurg Case Lessons
Tashiro R, Kawaguchi T, Izumi K, Ishida T, Watanabe H, Yamazaki Y, Endo H.   +6 more
europepmc   +1 more source