Results 191 to 200 of about 11,033,430 (362)
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Critical point theory in Hilbert space under general boundary conditions [PDF]
, 1965 E. H. Rothe
openalex +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Molecular Oncology, EarlyView.Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
Femtosecond control of phonon dynamics near a magnetic order critical point. [PDF]
Nat Commun, 2021 Gorobtsov OY +15 more
europepmc +1 more source
Critical-Point Behavior of the Susceptibility of Classical Heisenberg Ferrimagnets [PDF]
, 1968 Smith Freeman, Peter J. Wojtowicz
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
The Future of Stem Cells and Their Derivates in the Treatment of Glaucoma. A Critical Point of View. [PDF]
Int J Mol Sci, 2021 Nicoară SD +3 more
europepmc +1 more source
Light-Scattering Measurement of Concentration Fluctuations in Phenol-Water Near its Critical Point [PDF]
, 1969 P. N. Pusey, W. I. Goldburg
openalex +1 more source