A critical review of serum reactions from the view-point of diagnostics
Masayuki TAKATA
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Fault Critical Point Prediction Method of Nuclear Gate Valve with Small Samples Based on Characteristic Analysis of Operation. [PDF]
Liu Z+8 more
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Infection curves on small-world networks are linear only in the vicinity of the critical point. [PDF]
Kuśmierz Ł, Toyoizumi T.
europepmc +1 more source
Hysteresis-Loop Measurements of Critical-Point Exponents in Ferroelectrics
W. Reese
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Studies on the Electrophoretic Velocity of Colloidal Particles by the Moving Boundary Method. Part IV. Critical Study of the Influence of Dialysis on the Electrophoretic Velocity of Fe(OH)3 Sol and the Peak Point of the ζ-C Curve in the Aspect of Charge Density and Ionic Strength [PDF]
Arvind Kumar, Abani K. Bhattacharya
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TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
Critical Point-Finding Methods Reveal Gradient-Flat Regions of Deep Network Losses. [PDF]
Frye CG+5 more
europepmc +1 more source