Results 201 to 210 of about 11,033,430 (362)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Finite-size behaviour of a critical related observable

open access: yesOpen Physics, 2012
Yuanfang Wu   +4 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Ready or not, here we come: framing nutrition prescribing rights and responsibilities

open access: yesThe South African Journal of Clinical Nutrition
Lauren T Hill
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

A Brezis-Nirenberg problem on hyperbolic spaces

open access: yesElectronic Journal of Differential Equations, 2019
We consider a Brezis-Nirenberg problem on the hyperbolic space $\mathbb{H}^n$. By using the stereographic projection, the problem becomes a singular problem on the boundary of the open ball $B_1(0)\subset \mathbb{R}^n$. Thanks to the Hardy inequality,
Paulo C. Carriao   +3 more
doaj  

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