Results 151 to 160 of about 3,581,339 (338)

An Exposition on Critical Point Theory with Applications

open access: yesCurrent Research in Statistics & Mathematics
Critical Point Theory plays a pivotal role in the study of Partial Differential Equations (PDEs), particularly in investigating the existence, uniqueness, and multiplicity of weak solutions to elliptic PDEs under specified boundary conditions. This article offers a concise survey of key concepts, including differentiation on Banach spaces, the analysis
openaire   +1 more source

Not just a by‐product: circular DNA molecules derived from V(D)J recombination are linked to worse prognosis in B‐cell leukemia

open access: yesMolecular Oncology, EarlyView.
Gao et al. report that circular DNA molecules created as by‐products of V(D)J recombination during lymphocyte maturation (ESCs) can replicate and be retained for much longer than previously thought in healthy cells. In BCP‐ALL cells, increased ESC abundance correlates with a greater chance of relapse likely mediated by their ability to induce genome ...
Davide Pradella, Andrea Ventura
wiley   +1 more source

Rotationally invariant periodic solutions of semilinear wave equations

open access: yesAbstract and Applied Analysis, 1998
Martin Schechter
doaj   +1 more source

Existence of multiple solutions for quasilinear diagonal elliptic systems

open access: yesElectronic Journal of Differential Equations, 1999
Nonsmooth-critical-point theory is applied in proving multiplicity results for the quasilinear symmetric elliptic system $$ -sum_{i,j=1}^{n}D_j(a^{k}_{ij}(x,u)D_iu_k)+ {1over 2}sum_{i,j=1}^{n}sum_{h=1}^N D_{s_k}a^{h}_{ij}(x,u)D_iu_hD_ju_h=g_k(x,u ...
Marco Squassina
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

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