Results 131 to 140 of about 13,119,461 (251)

Rotationally invariant periodic solutions of semilinear wave equations

open access: yesAbstract and Applied Analysis, 1998
Martin Schechter
doaj   +1 more source

Existence of multiple solutions for quasilinear diagonal elliptic systems

open access: yesElectronic Journal of Differential Equations, 1999
Nonsmooth-critical-point theory is applied in proving multiplicity results for the quasilinear symmetric elliptic system $$ -sum_{i,j=1}^{n}D_j(a^{k}_{ij}(x,u)D_iu_k)+ {1over 2}sum_{i,j=1}^{n}sum_{h=1}^N D_{s_k}a^{h}_{ij}(x,u)D_iu_hD_ju_h=g_k(x,u ...
Marco Squassina
doaj  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Central Point Notice of Adopted Amendment (2008-12-29) [PDF]

open access: yes, 2008
162 pp. Adopted 2008-12-29. Department of Land Conservation and Development Notice of Adopted AmendmentThe attached proposed amendment is the Central Point Transportation System Plan (TSP) which will be an element of the updated Central Point ...
Central Point (Or.)
core  

Design of a planar gradient-index dielectric lens for arbitrary point-to-point beam focusing using critical-angle theory

open access: yesScientific Reports
This paper presents a novel analytical design method for a planar gradient-index (GRIN) dielectric lens based on the critical-angle theorem, capable of focusing electromagnetic waves between two arbitrarily located points.
Mohammad Mahdi Taskhiri   +2 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Jacques Lacan (Pre-published version)

open access: yes, 2017
Jacques Marie Émile Lacan was born on April 13, 1901 and died on September 9 1981. He was a French psychoanalyst and philosopher and was a very controversial figure on the French psychoanalytic scene.

core   +1 more source

On gamma-convergence for problems of jumping type

open access: yesElectronic Journal of Differential Equations, 2003
The convergence of critical values for a sequence of functionals $(f_h)$ $Gamma$-converging to a functional $f_{infty}$ is studied. These functionals are related to a classical ``jumping problem'', in which the position of two real parameters $alpha,eta$
Alessandro Groli
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

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