Results 1 to 10 of about 16,398,072 (267)

Differential Protein Expression among Two Different Ovine ARDS Phenotypes—A Preclinical Randomized Study

open access: yesMetabolites, 2022
Despite decades of comprehensive research, Acute Respiratory Distress Syndrome (ARDS) remains a disease with high mortality and morbidity worldwide. The discovery of inflammatory subphenotypes in human ARDS provides a new approach to study the disease ...
Karin Wildi   +15 more
doaj   +1 more source

Cryptanalysing the critical group: efficiently solving Biggs's discrete logarithm problem

open access: yesJournal of Mathematical Cryptology, 2009
Biggs has recently proposed the critical group of a certain class of finite graphs as a platform group for cryptosystems relying on the difficulty of the discrete log problem. The paper uses techniques from the theory of Picard groups on finite graphs to
Blackburn Simon R.
doaj   +1 more source

Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis

open access: yesSystematic Reviews, 2023
Introduction Shock-induced endotheliopathy (SHINE), defined as a profound sympathoadrenal hyperactivation in shock states leading to endothelial activation, glycocalyx damage, and eventual compromise of end-organ perfusion, was first described in 2017 ...
Nchafatso G. Obonyo   +10 more
doaj   +1 more source

Morse Thoery of Saddle Point Reduction with Applications

open access: yesAxioms
In this paper, we demonstrate that when saddle point reduction is applicable, there is a clear relationship between the Morse index and the critical groups before and after the reduction.
Ran Yang, Qin Xing
doaj   +1 more source

Small clique number graphs with three trivial critical ideals

open access: yesSpecial Matrices, 2018
The critical ideals of a graph are the determinantal ideals of the generalized Laplacian matrix associated to a graph. Previously, they have been used in the understanding and characterizing of the graphs with critical group with few invariant factors ...
Alfaro Carlos A., Valencia Carlos E.
doaj   +1 more source

Effect of flow change on brain injury during an experimental model of differential hypoxaemia in cardiogenic shock supported by extracorporeal membrane oxygenation

open access: yesScientific Reports, 2023
Differential hypoxaemia (DH) is common in patients supported by femoral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and can cause cerebral hypoxaemia. To date, no models have studied the direct impact of flow on cerebral damage.
Sacha Rozencwajg   +27 more
doaj   +1 more source

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin   +11 more
wiley   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

Characterizing preclinical sub‐phenotypic models of acute respiratory distress syndrome: An experimental ovine study

open access: yesPhysiological Reports, 2021
The acute respiratory distress syndrome (ARDS) describes a heterogenous population of patients with acute severe respiratory failure. However, contemporary advances have begun to identify distinct sub‐phenotypes that exist within its broader envelope ...
Jonathan E. Millar   +16 more
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier   +18 more
wiley   +1 more source

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