Results 241 to 250 of about 8,524,171 (298)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Critical Point

Acta Physica Polonica B Proceedings Supplement, 2017
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Why Bond Critical Points Are Not “Bond” Critical Points

Chemistry – A European Journal, 2018
AbstractEquating (3,−1) critical points (CPs), derived from the topological analysis of the electron densities, to chemical bonds has triggered a lot of confusion in recent years. Part of this confusion stems from calling these CPs “bond” CPs (BCPs). While the origin of this terminology is traceable to the late seventies and beginning of eighties, when
openaire   +2 more sources

The φ4 Critical Point

1981
To fix the notation, we consider the interaction $$V\left( \phi \right) = \lambda \phi ^4 + \sigma \phi ^2 - \mu \phi $$ (17.1.1) with λ, σ, and μ real and 0 0.)
James Glimm, Arthur Jaffe
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Critical Point in Complex Plasmas

Physical Review Letters, 2006
The occurrence of liquid-vapor phase transition and the possible existence of a critical point in complex plasmas--systems that consist of charged micrograins in a neutralizing plasma background--is investigated theoretically. An analysis based on the consideration of the intergrain interaction potential suggests that under certain conditions systems ...
Khrapak, S., Morfill, G., Ivlev, A., Thomas, H., Beysens, D., Zappoli, B., Fortov, V., Lipaev, A., Molotkov, V.   +8 more
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Percolation and critical points

Journal of Physics: Condensed Matter, 2001
The interplay between critical percolating clusters and critical points in physical systems and models is reviewed. The main emphasis is given to systems such as colloids and gels. Much information on the main mechanism leading to percolation in correlated systems can be obtained from the study of the Ising model.
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