Results 261 to 270 of about 847,794 (302)

Three-Dimensionally Printed Hyperelastic Bone Scaffolds Accelerate Bone Regeneration in Critical-Size Calvarial Bone Defects

Plastic & Reconstructive Surgery, 2019
Background: Autologous bone grafts remain the gold standard for craniofacial reconstruction despite limitations of donor-site availability and morbidity. A myriad of commercial bone substitutes and allografts are available, yet no product has gained widespread use because of inferior clinical outcomes. The ideal bone substitute
Yu-Hui, Huang, Adam E, Jakus, Sumanas W, Jordan, Zari, Dumanian, Kelly, Parker, Linping, Zhao, Pravin K, Patel, Ramille N, Shah   +7 more
openaire   +2 more sources

3D Printing in Treatment of Soft, Hard, and Critical-Sized Oral and Maxillofacial Tissue Defects

2021
Intraoral scanning, computer-aided object designing, and 3D printing, collectively known as digital workflow, are gradually becoming an indispensable procedure in modern dentistry. However, this approach has not yet been extensively investigated for the fabrication of oral and maxillofacial tissue substitutes.
Lobat Tayebi, Reza Masaeli, Kavosh Zandsalimi   +2 more
openaire   +1 more source

Three-Dimensional-Printed Spherical Hollow Structural Scaffolds for Guiding Critical-Sized Bone Regeneration

ACS Biomaterials Science & Engineering
The treatment of bone tissue defects continues to be a complex medical issue. Recently, three-dimensional (3D)-printed scaffold technology for bone tissue engineering (BTE) has emerged as an important therapeutic approach for bone defect repair. Despite the potential of BTE scaffolds to contribute to long-term bone reconstruction, there are certain ...
Xiao Liu, Jianpeng Gao, Jianheng Liu, Junyao Cheng, Zhenchuan Han, Zijian Li, Zhengyang Chang, Licheng Zhang, Ming Li, Peifu Tang   +9 more
openaire   +2 more sources

Three-dimensional printed strontium-containing mesoporous bioactive glass scaffolds for repairing rat critical-sized calvarial defects

Acta Biomaterialia, 2015
The development of a new generation of biomaterials with high osteogenic ability for fast osseointegration with host bone is being intensively investigated. In this study, we have fabricated three-dimensional (3-D) strontium-containing mesoporous bioactive glass (Sr-MBG) scaffolds by a 3-D printing technique.
Shichang, Zhao, Jianhua, Zhang, Min, Zhu, Yadong, Zhang, Zhongtang, Liu, Cuilian, Tao, Yufang, Zhu, Changqing, Zhang   +7 more
openaire   +2 more sources

Fabrication and Biological Activity of 3D-Printed Polycaprolactone/Magnesium Porous Scaffolds for Critical Size Bone Defect Repair

ACS Biomaterials Science & Engineering, 2020
Polycaprolactone (PCL) is widely used in bone tissue engineering due to its biocompatibility and mechanical strength. However, PCL is not biologically active and shows poor hydrophilicity, making it difficult for new bones to bind tightly to its surface.
Shuang Zhao, Kai Xie, Yu Guo, Jia Tan, Junxiang Wu, Yangzi Yang, Penghuai Fu, Lei Wang, Wenbo Jiang, Yongqiang Hao   +9 more
openaire   +2 more sources

A fully ingrowing implant for cranial reconstruction: Results in critical size defects in sheep using 3D-printed titanium scaffold

Biomaterials Advances, 2022
Current alloplastic materials such as PMMA, titanium or PEEK don't show relevant bone ingrowth into the implant when used for cranioplasty, ceramic implants have the drawback being brittle. New materials and implant designs are urgently needed being biocompatible, stable enough for cranioplasty and stimulating bone formation.
Hubbe, Ulrich, Beiser, Svea, Kuhn, Sascha, Stark, Tobias, Hoess, Angelika, Cristina-Schmitz, Heidi, Vasilikos, Ioannis, Metzger, Marc Christian, Rothweiler, René   +8 more
openaire   +3 more sources

3D printing of strontium-doped hydroxyapatite based composite scaffolds for repairing critical-sized rabbit calvarial defects

Biomedical Materials, 2018
In this study, strontium substituted hydroxyapatite (Sr-HAP) was synthesized using collagen type I and citrate as bi-templates and the obtained nanoparticles with high similarity to natural bone minerals were made into composite scaffolds with interconnected porous structure using a three-dimensional (3D) printing technique.
Yun Luo, Shangsi Chen, Yufei Shi, Jun Ma
openaire   +2 more sources

Three-Year Follow-Up of a Traumatic Critical-Sized Tibial Bone Defect Treated with a 3D Printed Titanium Cage

JBJS Case Connector, 2023
Case: We report a case involving a 21-year-old woman who sustained a Grade III open pilon fracture of the left ankle during a motor vehicle accident that resulted in a 12-cm critical-sized bone defect (CSD) that was successfully treated with a three-dimensional (3D) printed titanium alloy (Ti-6Al-4V) cage, a tibiotalocalcaneal ...
Lindsey G. Johnson, Molly M. Kearney, Nicholas B. Allen, Samuel B. Adams   +3 more
openaire   +2 more sources

3D-printed polymeric scaffolds with optimized architecture to repair a sheep metatarsal critical-size bone defect

2022
AbstractThe reconstruction of critical-size bone defects in long bones remains a challenge for clinicians. We developed a new bioactive medical device for long bone repair by combining a 3D-printed architectured cylindrical scaffold made of clinical-grade polylactic acid (PLA) with a polyelectrolyte film coating delivering the osteogenic bone ...
Charlotte Garot, Sarah Schoffit, Cécile Monfoulet, Paul Machillot, Claire Deroy, Samantha Roques, Julie Vial, Julien Vollaire, Martine Renard, Hasan Ghanem, Hanane El-Hafci, Adeline Decambron, Véronique Josserand, Laurence Bordenave, Georges Bettega, Marlène Durand, Mathieu Manassero, Véronique Viateau, Delphine Logeart-Avramoglou, Catherine Picart   +19 more
openaire   +1 more source

Layered Antimicrobial Selenium Nanoparticle–Calcium Phosphate Coating on 3D Printed Scaffolds Enhanced Bone Formation in Critical Size Defects

ACS Applied Materials & Interfaces, 2020
Preventing bacterial colonization on scaffolds while supporting tissue formation is highly desirable in tissue engineering as bacterial infection remains a clinically significant risk to any implanted biomaterials. Elemental selenium (Se0) nanoparticles have emerged as a promising antimicrobial biomaterial without tissue cell toxicity, yet it remains ...
Cedryck Vaquette, Nathalie Bock, Phong A. Tran   +2 more
openaire   +3 more sources