Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Synergistic effects of ultrasound and stirring on crystallization behavior of coconut oil: Physicochemical properties, crystallinity and potential mechanism. [PDF]
Yang H, Fu Y, Xu S, Xue J, Cao J.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Recent Advancements in Gel-Based Flexible Electronic Sensors. [PDF]
Kumar V, Park SS.
europepmc +1 more source
Variation of Fluid Properties for Carbon Dioxide and Methane under High Temperature (16 ∼ 200 °C) and High Pressure (5 ∼ 100 MPa). [PDF]
Jiang P, Liao J, Wang X, Pan L, Guo C.
europepmc +1 more source
Synergetic properties of advanced materials for high-power and high-temperature applications. [PDF]
Mengesha WG, Nagessar K.
europepmc +1 more source
Critical shifts of fluids in shale nanopores under confinement effects using a modified Redlich Kwong equation of state. [PDF]
Zhou B, Wu X, Li B, Li J.
europepmc +1 more source
A critical review of chemical heterogeneity-driven microstructure control in steels. [PDF]
Lee SH, Kim JH.
europepmc +1 more source

