Results 51 to 60 of about 34,532 (296)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
, 2012 Critical realism has become increasingly well known in the social sciences, particularly for its trenchant critiques of forms of idealism such as positivism and interpretivism. Rarely, however, has critical realism itself been subjected to critique. This article argues that realism and idealism are just two sides of the same foundationalist coin, with ...
openaire +3 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Bringing critical realism to Nursing Practice: Roy Bhaskar's Contribution [PDF]
, 2016 In the context of modern nursing practice which is embedded within complex social situations, critical discussions about the contribution of major philosophers are relevant and important.
Rycroft-Malone, Joanne +5 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A critical 'post' to critical realism
, 2002 The aim of this paper is to initiate a dialogue between critical realism (CR) and what is termed a ‘post'ist perspective’. This amalgamated perspective is composed of relatively recent transdisciplinary theoretical approaches such as poststructuralism ...
Kaul, N.
core +1 more source
Whatever happened to curriculum theory? Critical realism and curriculum change [PDF]
, 2011 In the face of what has been characterised as a ‘crisis’ in curriculum – an apparent decline of some aspects of curriculum studies combined with the emergence of new types of national curriculum which downgrade knowledge – some writers have been arguing ...
Priestley, Mark, Mark Priestley
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Management Knowledge and Knowledge Management: Realism and Forms of Truth [PDF]
, 2008 This paper addresses the issue of truth and knowledge in management generally and knowledge management in particular. Based on ideas from critical realism and critical theory, it argues against the monovalent conceptualization of knowledge implicitly or ...
Mingers, John, John Mingers
core +1 more source
BJPsych BulletinIn this opinion article, we discuss the application of critical realism as an alternative model to the biopsychosocial model in the understanding of psychiatric disorders.
Mohammed Al Alawi +2 more
doaj +1 more source