Results 71 to 80 of about 34,532 (296)
Colonial Trauma in Márquez and Rushdie’s Magical Realism [PDF]
, 2015 Gabriel García Márquez’s One Hundred Years of Solitude and Salman Rushdie’s Midnight’s Children are hallmarks of the genre of magical realism. A typically problematic genre in terms of classification, this article looks at magical realism from a Freudian
Miller, Rachel
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"Critical Realism and the Political Economy of the Euro" [PDF]
This paper is concerned with two issues. First, it discusses some of the main problems and inferences the methodological approach of critical realism raises for empirical work in economics, while considering an approach adopted to try to overcome these ...
Malcolm Sawyer +2 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
DEBATE: Kant, ontology and empirical realism: Response to Assiter [PDF]
, 2015 In this debate article I respond to Alison Assiter’s various objections and points regarding my work on Kant’s empirical realism, his relation to ontology, and related issues.
McWherter, Dustin
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, 2022 This paper considers the utility of critical realism as an ontological foundation for the analysis of education policy in emergencies. By exploring the synergy between critical realism and a method to analyse policy known as Critical Policy Analysis, the
Couch, Daniel
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Critical Realism versus Social Constructivism in International Relations [PDF]
The Journal of Philosophical Economics, 2011 This article discusses the methodological differences between the British school and the American school of international relations. It attempts to demonstrate that Susan Strange, representative of the British school, could be considered a critical ...
Roxana Bobulescu
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
A Defence of Informational Structural Realism [PDF]
, 2007 This is the revised version of an invited keynote lecture delivered at the 1st Australian Computing and Philosophy Conference (CAP@AU; the Australian National University in Canberra, 31 October – 2 November, 2003).
Luciano Floridi +2 more
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source