Results 81 to 90 of about 34,532 (296)

What we can learn from the former workers of a Vietnamese state farm to understand privatised employment-based pension systems : engaging with critical realism?

open access: yes, 2005
This paper first revisits the discussion between Tony Lawson and Sandra Harding in the journal Feminist Economics in light of the author’s own research into basic mechanisms of capitalist economies, research that has been influenced by feminist ...
Brown, G.   +2 more
core  

Crítica e cultura em marketing: repensando a disciplina

open access: yesCadernos EBAPE.BR
Este artigo descreve o processo de implementação de uma abordagem crítica em marketing, baseada no realismo crítico e desenvolvida na Inglaterra e no Brasil por um pesquisador brasileiro.
Alexandre Faria
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Critical realism: a methodological design for destination food image research

open access: yes, 2022
This paper provides a critical realist reflection on methodological decisions that frame examination of the effectiveness of destination branding using food and cuisine. The authors use a multi-method strategy to evaluate the degree of congruence amongst
Lai, Mun Yee, Wang, Ying, Khoo, Catheryn
core   +1 more source

Critical Realism: Philosophical Origin and Methodological Principles [PDF]

open access: yesIslām va ̒ulūm-i ijtimā̒ī
During the past few decades, social sciences and humanities has been involved in numerous methodological and theoretical debates that is described as the paradigms war between positivists, interpretativists and critics.
Ahmad Mohammad Poor   +2 more
doaj  

Asking “How” and “Why” and “Under What Conditions” Questions: Using Critical Realism to Study Learning and Teaching

open access: yesTeaching & Learning Inquiry: The ISSOTL Journal
Research paradigms offer a way for scholars to design, communicate, and reflect on their research effectively. A paradigm encapsulates the researcher’s worldview, including the epistemology, ontology, and axiology of the research.
Janice Miller-Young
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Left Realism: A Radical Criminology for the Current Crisis

open access: yesInternational Journal for Crime, Justice and Social Democracy, 2016
The renewal of the Left realist tradition in criminology is vital for a critical understanding of crime and criminal justice in the context of a dominant neoliberalism. Left Realism presented two core components: the local democratic community control of
John Lea
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy