Results 101 to 110 of about 34,532 (296)
Teaching What Is "Real" About Science: Critical Realism as a Framework for Science Education. [PDF]
Ferguson SL.
europepmc +1 more source
Critical realism is underpinned by the ontology of natural necessity. This ontology cannot be derived from empirical fact. It is deduced, transcendentally, from the intelligibility of intentional activity.
Brown, G., Moussa, Margaret
core
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Applying critical realism to the COVID-19 pandemic to improve management of future public health crises. [PDF]
Correia T, Willis K.
europepmc +1 more source
Explanations of British industrial decline : a critical realist perspective
The phenomenon of British industrial decline has attracted a massive range of analysis and explanatory argument. My intention here is to assess the explanatory power of several prominent explanations using some of the concepts of critical realism.
Brown, G., Nalson, Ian, Moussa, Margaret
core
The Argument from Underconsideration and Relative Realism [PDF]
In this paper, through a critical examination of Wray’s version of the argument from underconsideration against scientific realism, I articulate a modest version of scientific realism.
Mizrahi, Moti
core
A return to common-sense: why ecology needs transcendental realism
Empirical realist ecologists, such as C. S. Holling, face significant methodological contradictions; for instance, they must cope with the problem that ecological models and theories of climate change, resilience and succession cannot make predictions in
Price, Leigh
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Queer Genes: Realism, Sexuality and Science
What are ‘gay genes’ and are they real? This article looks at key research into these hypothesized gay genes, made possible, in part, by the Human Genome Project.
Griffiths, David
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source

