Results 91 to 100 of about 4,716,782 (236)
"Critical Realism and the Political Economy of the Euro" [PDF]
This paper is concerned with two issues. First, it discusses some of the main problems and inferences the methodological approach of critical realism raises for empirical work in economics, while considering an approach adopted to try to overcome these ...
Malcolm Sawyer +2 more
core
Moderate structural realism about space-time [PDF]
This paper sets out a moderate version of metaphysical structural realism that stands in contrast to both the epistemic structural realism of Worrall and the – radical – ontic structural realism of French and Ladyman.
Lam, Vincent +3 more
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Beyond Capitalist Realism – Why We Need Critical Future Studies
This paper introduces the interdisciplinary field of Critical Future Studies (CFS). CFS investigates the scope and constraints within public culture for imagining and debating different potential futures.
Luke Goode, Michael Godhe
doaj +1 more source
Management Knowledge and Knowledge Management: Realism and Forms of Truth [PDF]
This paper addresses the issue of truth and knowledge in management generally and knowledge management in particular. Based on ideas from critical realism and critical theory, it argues against the monovalent conceptualization of knowledge implicitly or ...
Mingers, John, John Mingers
core +3 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
International human rights, citizenship education, and critical realism
Citizenship education invokes dilemmas even for the most committed teachers and students, researchers, and innovators. How can citizenship education advance equity and equal rights within highly unequal schools and societies?
doaj +2 more sources
Left Realism: A Radical Criminology for the Current Crisis
The renewal of the Left realist tradition in criminology is vital for a critical understanding of crime and criminal justice in the context of a dominant neoliberalism. Left Realism presented two core components: the local democratic community control of
John Lea
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source

