Results 101 to 110 of about 559,557 (278)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Carry On, Cowboy: roast beef Westerns [PDF]
, 2012 Most critical discussions of non-American Westerns have centred on films by Italian and German filmmakers, such as Sergio Leone and Harald Reinl. There has, however, been little attention paid to the Westerns produced by British companies and British ...
Hall, Sheldon
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Critical reception of Umbral in the histories of the novel [PDF]
, 2017 Me propongo rastrear el tratamiento de la obra de Francisco Umbral en uno de los ámbitos de la crítica literaria que considero especialmente relevante: el de las historias de la literatura y, específicamente en este caso, el género novela.
Barrero Pérez, Óscar
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Sophie Heywood, Catholicism and Chidren’s Literature in France. The comtesse de Ségur (1799-1874)
Strenae, 2012 Rémi Saudray
doaj +1 more source
The 1985 Chile earthquake: Structural characteristics and damage statistics for the building inventory in Vina del Mar [PDF]
, 1987 The Chile earthquake of 3 March 1985 resulted in an effective peak acceleration of 0.36g in the coastal city of Vina del Mar. The city had an inventory of over 400 reinforced concrete buildings ranging in height from 5 to 23 stories.
de la Llera, J.C. +2 more
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Reception Frame of Iris Murdoch’s Critical Studies
Pitannâ Lìteraturoznavstva, 2018 The article analyzes the enrichment of the reception frame of I. Murdoch's oeuvre due to the complementation of different discourses (fiction, philosophy, culture study, criticism and theory of literature).
Aliona Matiychak
doaj