Results 121 to 130 of about 6,302,669 (265)
Acoustic Anomalies and the Critical Slowing-Down Behavior of MAPbCl3 Single Crystals Studied by Brillouin Light Scattering. [PDF]
Materials (Basel), 2022 Lee JW, Naqvi FH, Ko JH, Kim TH, Ahn CW.
europepmc +1 more source
Observation of critical slowing down close to a roughening transition
, 1983 We have measured the times necessary to recover the stable size of a facet of a 4He crystal in a slow growing process, close to the roughening transition of the facet (TR ≅ 215 mK). These times exhibit a critical slowing down from 2 min.
B. Hebral +3 more
core +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Critical slowing down suggests that the western Greenland Ice Sheet is close to a tipping point. [PDF]
Proc Natl Acad Sci U S A, 2021 Boers N, Rypdal M.
europepmc +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Earth's FutureThe Amazon rainforest (ARF) is threatened by deforestation and climate change, which could trigger a regime shift to a savanna‐like state. Whilst previous work has suggested that forest resilience has declined in recent decades, that work was based only ...
Lana L. Blaschke +6 more
doaj +1 more source
Coriolis acceleration and critical slowing-down : a quantitative laboratory experiment
International audienceWe experimentally investigate the motion of a pendulum on a turntable. The dynamics of this conical pendulum experiment are very rich and can be studied both at the undergraduate and graduate levels.
Combe, Nicolas +4 more
core +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
FEBS Open Bio, EarlyView.Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
FEBS Open Bio, EarlyView.This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source