Results 101 to 110 of about 6,302,669 (265)
From Phonons to Domain Walls, the Central Peak and “Critical Slowing Down”
Condensed MatterWe investigate perovskite oxides from different perspectives, namely their pseudo-harmonic dynamical properties, their dynamical properties when strong anharmonicity exists, and the intriguing functionalities arising from domain walls.
Ekhard K. H. Salje +1 more
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Predicting Dike Piping Hazards Using Critical Slowing Down Theory on Electrical Signals
Applied SciencesEarly warning signals of critical transitions in the piping process are essential for predicting dike hazards. This study proposes a new approach that combines Critical Slowing Down (CSD) theory with electrical signals analysis to identify precursor ...
Tongtong Wang, Yuan Wang, Jie Ren
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Defeating critical slowing down for abelian gauge dynamics
, 1992 Using the Connection Machine CM-2 we investigate critical slowing down for the multi-scale update algorithm (MSU) for abelian gauge theories recently proposed by two of the present authors.
Schilling, Klaus +4 more
core +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Critical slowing down near a magnetic quantum phase transition with fermionic breakdown. [PDF]
Nat Phys, 2023 Yang CJ +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Critical slowing down may account for the robustness of development. [PDF]
Proc Natl Acad Sci U S A, 2022 Zhang W, Scerbo P, Ducos B, Bensimon D.
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source