Results 41 to 50 of about 556,544 (304)

Critical success factors in e-learning for small and medium enterprises [PDF]

open access: yes, 2009
In 2008 the Ministry of Education in New Zealand funded a project titled Using e-learning to build workforce capability (Clayton, Elliott, Saravani, Greene & Huntington, 2008).
Clayton, John, Elliott, Richard
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Professional development of teachers: Critical success factors

open access: yesKoers : Bulletin for Christian Scholarship, 2005
Professional development (PD) has attracted a great deal of attention in recent years. Despite research findings, the development of many PD programmes often rests on faulty assumptions of such research or even no research at all.
G.M. Steyn, L.J. van Niekerk
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Critical Success Factors in Construction Projects (Governmental Projects as a Case Study)

open access: yesJournal of Engineering, 2016
The importance of the construction sector and its Great role in the provision of services and infrastructure, reduce poverty, improve living conditions and improve the economic situation in the country, impose attention to the way in which the projects ...
Hatem Khaleefah Al-Ageeli, Ass. Prof. Dr.   +1 more
doaj  

CRITICAL SUCCESS FACTORS AND PERFORMANCE OF FIBRE OPTIC INFRASTUCTURE PROJECTS BY INFORMATION AND COMMUNICATION TECHNOLOGY AUTHORITY, KENYA

open access: yes, 2023
: Information Communication and Technology is crucial to Kenya’s economy since it fosters growth and gives the country’s economy a boost. The study focused on the effect of critical success factors and performance of fibre optic infrastructure projects ...
Allan Kabiru Ngugi, Morrisson Mutuku
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Project success/failure rates in Turkey

open access: yesInternational Journal of Information Systems and Project Management, 2021
In this study, the success rate of projects in Turkey is measured, and the significant factors behind the successes and the failures of those projects are ranked.
Canser Istanbul Sabahattin Zaim Universitesi   +4 more
doaj   +1 more source

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