Treatment decision-making for leptomeningeal metastasis after TKI resistance in EGFR-mutant lung cancer: a comprehensive review on staging, resistance patterns, and multimodal interventions. [PDF]
Song GQ, He TL, Ji KJ, Duan YM, Hu GQ.
europepmc +1 more source
Exploring critical success factors of knowledge management projects in the consulting sector
Knowledge management (KM) and critical success factors (CSFs) are interesting issues in the current business world. Knowledge is an important driving force for business success and competiveness, especially in the consulting industry whose core business ...
Mas Machuca, Marta +1 more
core
ABSTRACT In a large multicenter real‐world cohort, we aimed to evaluate outcomes of FLAG‐Ida salvage therapy for relapsed/refractory (R/R) acute myeloid leukemia (AML) and validated the SALFLAGE prognostic score. We analyzed 1079 adults with R/R AML treated across 112 PETHEMA institutions over 26 years (1998–2024), including patients with primary ...
Gaspar Aspas Requena +49 more
wiley +1 more source
Potential role of standardized orbital ultrasound in the management of spontaneous CSF leaks. [PDF]
Rigante M +10 more
europepmc +1 more source
Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Critical success factors influencing business intelligence adoption: Evidence from Yemen. [PDF]
Al-Adimi AT +3 more
europepmc +1 more source
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
G-CSF for Mobilizing CD34<sup>+</sup> Cells in Individuals With SCD: A Word of Caution. [PDF]
Sharma A +17 more
europepmc +1 more source
This review evaluates the clinical potential and limitations of intranasal (IN) drug administration in veterinary anaesthesia and emergency care. IN delivery can provide clinically relevant sedation, analgesia and drug reversal, but its success is not universally reliable and is strongly influenced by species‐specific anatomy, formulation ...
Majid Jafarbeglou
wiley +1 more source
Comprehensive review of the cerebral aqueduct: anatomy, embryology, imaging, genetics, molecular, and pathology. [PDF]
Dituri G +11 more
europepmc +1 more source

