Results 251 to 260 of about 3,824,363 (314)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Functional stability assessment and adaptation for critical infrastructure facilities. [PDF]

Front Artif Intell
Perederyi V, Borchik E, Zosimov V, Bulgakova O.   +3 more
europepmc   +1 more source

Rurality and long-term outcomes after critical illness. [PDF]

Ann Am Thorac Soc
Mart MF, Jones MT, Raman R, Stinehart KR, Mayer KP, Jackson JC, Pandharipande PP, Su H, Boehm LM, Ely EW, Brummel NE.   +10 more
europepmc   +1 more source

Robotic-assisted pedicle screw placement achieves high accuracy and narrows the experience gap: a preclinical evaluation. [PDF]

J Robot Surg
Reza AT, Walper M, Ng MK, Mastrokostas PG, Lee AS, de Oliveira RG, Poelstra KA, Ratliff JK, Sethi RK, Mont MA.   +9 more
europepmc   +1 more source

Conversion of waste cooking oil to environmentally acceptable surfactants for enhanced oil recovery. [PDF]

Sci Rep
Al Sabagh AM, Abdel-Salam FH, Mohamed A.
europepmc   +1 more source

Deforestation-induced drying lowers Amazon climate threshold. [PDF]

Nature
Wunderling N, Sakschewski B, Rockström J, Flores BM, Hirota M, Staal A.   +5 more
europepmc   +1 more source

Why forensic scientists are essential workers. [PDF]

Forensic Sci Int Synerg
Houck MM, LaBerge GS.
europepmc   +1 more source

Investigation of the Crystallization Region for High-Quality GaN Growth in Na-Flux Method. [PDF]

ACS Omega
Yao J, Yang Z, Zhou M, Wang X, Yang S, Wan Q, Yang X, Zhao J, Li Z, Xiong Z.   +9 more
europepmc   +1 more source